Efficient synthesis of β,γ-alkynyl α-amino acid derivatives by Ag(I)-catalyzed alkynylation of α-imino esters

被引：72
|
作者：
Ji, JX
Au-Yeung, TL
Wu, J
Yip, CW
Chan, ASC [1 ]
机构：
[1] Hong Kong Polytech Univ, Inst Mol Technol Drug Discovery, Open Lab Chirotechnol, Hong Kong, Hong Kong, Peoples R China
[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2004年 / 346卷 / 01期
关键词：
alkynes; alpha-amino acids; alpha-imino ester; catalytic synthesis; silver(I) salt;
D O I：
10.1002/adsc.200303148
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The first catalytic synthesis of beta,gamma-alkynyl alpha-amino acid derivatives was achieved by direct addition of terminal alkynes to alpha-imino esters in the presence of an Ag(I) salt under mild reaction conditions.
引用
收藏
页码：42 / 44
页数：3
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