Recent advances in electrospun nanofibers for some biomedical applications

被引：77
|
作者：
Sabra, Sally [1 ]
Ragab, Doaa M. [2 ,3 ]
Agwa, Mona M. [4 ]
Rohani, Sohrab [2 ]
机构：
[1] Alexandria Univ, Inst Grad Studies & Res, Dept Biotechnol, Alexandria, Egypt
[2] Univ Western Ontario, Fac Engn, Dept Chem & Biochem Engn, London, ON, Canada
[3] Alexandria Univ, Fac Pharm, Dept Ind Pharm, Alexandria, Egypt
[4] Natl Res Ctr, Dept Chem Nat & Microbial Prod, Cairo, Egypt
来源：
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2020年 / 144卷
关键词：
Nanofibers; Electrospinning; Wound healing; Herbal extracts; Antimicrobial peptides; Skin cancer; Growth factors; GROWTH-FACTOR DELIVERY; DRUG-DELIVERY; ANTIMICROBIAL PEPTIDES; DUAL-DELIVERY; IN-VITRO; PHOTOTHERMAL ABLATION; SALVIA-MILTIORRHIZA; SCAFFOLDS; RELEASE; ANTIOXIDANT;
D O I：
10.1016/j.ejps.2020.105224
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Nanofibers provide multiple merits for the delivery of many therapeutic agents with versatile biomedical applications. With the fast recent advancement in nanotechnology, nanofibers could be easily fabricated with tunable morphologies and release profiles. Here, we review the most recent approaches in the fabrication of electrospun nanofibers incorporating some natural ingredients for their wound healing potential. In addition, electrospun nanofibers for treatment of skin carcinoma and delivery of different growth factors for tissue regeneration will also be highlighted in this review. Nanofibers incorporating different active therapeutical agents are very promising drug delivery platforms.
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页数：22
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