Heterogeneous Catalytic Hydrogenation Reactions in Continuous-Flow Reactors

被引：304
|
作者：
Irfan, Muhammad [1 ,2 ]
Glasnov, Toma N. [1 ,2 ]
Kappe, C. Oliver [1 ,2 ]
机构：
[1] Karl Franzens Univ Graz, CDLMC, A-8010 Graz, Austria
[2] Karl Franzens Univ Graz, Inst Chem, A-8010 Graz, Austria
来源：
CHEMSUSCHEM | 2011年 / 4卷 / 03期
关键词：
flow chemistry; heterogeneous catalysis; hydrogenation; microreactors; process intensification; CONTINUOUS ENANTIOSELECTIVE HYDROGENATION; FIXED-BED REACTOR; SUPERCRITICAL CARBON-DIOXIDE; ENANTIO-SELECTIVE HYDROGENATION; TRANSITION-METAL-COMPLEXES; LIQUID-PHASE HYDROGENATION; PROTECTING GROUP REMOVAL; ETHYL PYRUVATE; HIGH-PRESSURE; ASYMMETRIC HYDROGENATION;
D O I：
10.1002/cssc.201000354
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Microreactor technology and continuous flow processing in general are key features in making organic synthesis both more economical and environmentally friendly. Heterogeneous catalytic hydrogenation reactions under continuous flow conditions offer significant benefits compared to batch processes which are related to the unique gas-liquid-solid triphasic reaction conditions present in these transformations. In this review article recent developments in continuous flow heterogeneous catalytic hydrogenation reactions using molecular hydrogen are summarized. Available flow hydrogenation techniques, reactors, commonly used catalysts and examples of synthetic applications with an emphasis on laboratory-scale flow hydrogenation reactions are presented.
引用
收藏
页码：300 / 316
页数：17
相关论文
共 50 条
  • [41] Catalytic determination of rhodium in a continuous-flow system
    Khomutova, EG
    Rysev, AP
    Fedorina, LI
    [J]. JOURNAL OF ANALYTICAL CHEMISTRY, 1997, 52 (07) : 683 - 686
  • [42] Structuring hybrid palladium nanoparticles in metallic monolithic reactors for continuous-flow three-phase alkyne hydrogenation
    Albani, Davide
    Vile, Gianvito
    Toro, Mario Alejandro Beltran
    Kaufmann, Rolf
    Mitchell, Sharon
    Perez-Ramirez, Javier
    [J]. REACTION CHEMISTRY & ENGINEERING, 2016, 1 (04): : 454 - 462
  • [43] Redox reactions in potentiometric continuous-flow analysis
    Sorokina, NV
    Urusov, YI
    Petrukhin, OM
    [J]. JOURNAL OF ANALYTICAL CHEMISTRY, 1996, 51 (09) : 851 - 854
  • [44] Continuous-flow photochemical carbene transfer reactions
    Claire Empel
    Rene M. Koenigs
    [J]. Journal of Flow Chemistry, 2020, 10 : 157 - 160
  • [45] Three-phase catalytic reactors for hydrogenation and oxidation reactions
    Joseph, Wood
    [J]. PHYSICAL SCIENCES REVIEWS, 2016, 1 (01)
  • [46] Continuous-flow photochemical carbene transfer reactions
    Empel, Claire
    Koenigs, Rene M.
    [J]. JOURNAL OF FLOW CHEMISTRY, 2020, 10 (01) : 157 - 160
  • [47] Redox Reactions in Potentiometric Continuous-Flow Analysis
    [J]. J Anal Chem, 9 (851):
  • [48] The temperature hysteresis in exothermic heterogeneous catalytic reactions of hydrogenation
    Gudkov, BS
    Subbotin, AN
    Yakerson, VI
    [J]. DOKLADY AKADEMII NAUK, 1999, 364 (06) : 786 - 788
  • [49] KINETICS OF HETEROGENEOUS REACTIONS WITH SPECIAL REFERENCE TO CATALYTIC HYDROGENATION
    FUZEK, JF
    SMITH, HA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1948, 70 (11) : 3743 - 3745
  • [50] Model studies of heterogeneous catalytic hydrogenation reactions with gold
    Pan, Ming
    Brush, Adrian J.
    Pozun, Zachary D.
    Ham, Hyung Chul
    Yu, Wen-Yueh
    Henkelman, Graeme
    Hwang, Gyeong S.
    Mullins, C. Buddie
    [J]. CHEMICAL SOCIETY REVIEWS, 2013, 42 (12) : 5002 - 5013
12345