Infection, autoimmunity, and glycolipids: T cells detect microbes through self-recognition

被引：14
|
作者：
Kronenberg, M [1 ]
Kinjo, Y [1 ]
机构：
[1] La Jolla Inst Allergy & Immunol, San Diego, CA 92121 USA
来源：
IMMUNITY | 2005年 / 22卷 / 06期
关键词：
D O I：
10.1016/j.immuni.2005.06.001
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
De Libero et al. (2005) demonstrate in this issue of Immunity that bacterial infection leads to increased synthesis of autologous glycolipids that are recognized by CD1-restricted human T cells, indicating that recognition of inducible self-glycolipids could be a mechanism for microbial detection. This mechanism also may provide a connection between infection and autoimmunity.
引用
收藏
页码：657 / 659
页数：3
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