Infection, autoimmunity, and glycolipids: T cells detect microbes through self-recognition

被引：14
|
作者：
Kronenberg, M [1 ]
Kinjo, Y [1 ]
机构：
[1] La Jolla Inst Allergy & Immunol, San Diego, CA 92121 USA
来源：
IMMUNITY | 2005年 / 22卷 / 06期
关键词：
D O I：
10.1016/j.immuni.2005.06.001
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
De Libero et al. (2005) demonstrate in this issue of Immunity that bacterial infection leads to increased synthesis of autologous glycolipids that are recognized by CD1-restricted human T cells, indicating that recognition of inducible self-glycolipids could be a mechanism for microbial detection. This mechanism also may provide a connection between infection and autoimmunity.
引用
收藏
页码：657 / 659
页数：3
相关论文
共 50 条
  • [1] SELF-RECOGNITION, AUTOIMMUNITY, AND INTERNAL IMAGES
    ZANETTI, M
    KATZ, DH
    [J]. CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY, 1985, 119 : 111 - 126
  • [2] Recognition of self and altered self by T cells in autoimmunity and allergy
    Yin, Lei
    Dai, Shaodong
    Clayton, Gina
    Gao, Wei
    Wang, Yang
    Kappler, John
    Marrack, Philippa
    [J]. PROTEIN & CELL, 2013, 4 (01) : 8 - 16
  • [3] Recognition of self and altered self by T cells in autoimmunity and allergy
    Lei Yin
    Shaodong Dai
    Gina Clayton
    Wei Gao
    Yang Wang
    John Kappler
    Philippa Marrack
    [J]. Protein & Cell, 2013, 4 (01) : 8 - 16
  • [4] THE BASIS OF AUTOIMMUNITY .1. MECHANISMS OF ABERRANT SELF-RECOGNITION
    THEOFILOPOULOS, AN
    [J]. IMMUNOLOGY TODAY, 1995, 16 (02): : 90 - 98
  • [5] 'Self-recognition' by natural killer cells
    Held, W.
    [J]. IMMUNOLOGY, 2008, 125 : 12 - 12
  • [6] SIGNIFICANCE OF SELF-RECOGNITION AND INTERLEUKIN-2 FOR IMMUNOREGULATION, AUTOIMMUNITY AND CANCER
    SMITH, JB
    TALAL, N
    [J]. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1982, 16 (04) : 269 - 278
  • [7] Adaptive tolerance: Protection through self-recognition
    Amendt, Timm
    Jumaa, Hassan
    [J]. BIOESSAYS, 2022, 44 (03)
  • [8] Self-recognition of CD1 by γ/δ T cells:: Implications for innate immunity
    Spada, FM
    Grant, EP
    Peters, PJ
    Sugita, M
    Melián, A
    Leslie, DS
    Lee, HK
    van Donselaar, E
    Hanson, DA
    Krensky, AM
    Majdic, O
    Porcelli, SA
    Morita, CT
    Brenner, MB
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (06): : 937 - 948
  • [9] T Cell's Sense of Self: a Role of Self-Recognition in Shaping Functional Competence of Naive T Cells
    Kim, Hee-Ok
    Cho, Jae-Ho
    [J]. IMMUNE NETWORK, 2017, 17 (04) : 201 - 213
  • [10] γδ T cells in infection and autoimmunity
    Hou, Lifei
    Wang, Tian
    Sun, Jiaren
    [J]. INTERNATIONAL IMMUNOPHARMACOLOGY, 2015, 28 (02) : 887 - 891
12345