South Portuguese population data on the loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc

Five South Portuguese Caucasian subpopulations were analyzed for the HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Cc loci. Genotype distributions for these loci did not deviate from Hardy-Weinberg expectations. The allele and genotype frequencies found have been compared with previously published data from North and Central Portugal. A total of 11 out of 138 chi-square comparisons of allele frequencies between different Portuguese populations showed a certain degree of divergence. Alentejo, Algarve, Madeira Island and Azores Islands populations might be considered as different groups in a database. For forensic casework, a composite South Portuguese Caucasian population database was obtained for estimating multiple locus profile frequencies using the six PCR-based loci studied.