PATHOLOGY AND BIOLOGY;
ARAB;
POPULATION DATABASES;
POLYMERASE CHAIN REACTION;
HARDY-WEINBERG;
HLA-DQA1;
LDLR;
GYPA;
HBGG;
D7S8;
GC;
D1S80;
D O I:
暂无
中图分类号:
DF [法律];
D9 [法律];
R [医药、卫生];
学科分类号:
0301 ;
10 ;
摘要:
Allele and genotype frequencies for seven polymerase chain reaction (PCR)-based DNA genetic markers were determined in an Arab sample population. The loci analyzed were HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc and D1S80. Results were obtained from the first six loci using the AmpliType HLA-DQ alpha DNA and AmpliType PM PCR Amplification and Typing Kits. The VNTR locus D1S80 PCR product was analyzed by polyacrylamide electrophoresis and silver staining. All loci meet Hardy-Weinberg expectations. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in the Arab population.