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Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol & Blood Dis Hosp, Haihe Lab Cell Ecosyst, Natl Clin Res Ctr Blood Dis,State Key Lab Expt He, Tianjin, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol & Blood Dis Hosp, Haihe Lab Cell Ecosyst, Natl Clin Res Ctr Blood Dis,State Key Lab Expt He, Tianjin, Peoples R China