A double-enhanced strip biosensor for the rapid and ultrasensitive detection of protein biomarkers

被引：16
|
作者：
Qin, Chunyan
Wen, Wei
Zhang, Xiuhua
Gu, Haoshuang
Wang, Shengfu [1 ]
机构：
[1] Hubei Univ, Minist Educ, Key Lab Synth & Applicat Organ Funct Mol, Hubei Collaborat Innovat Ctr Adv Organ Chem Mat, Wuhan 430062, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 39期
基金：
中国国家自然科学基金;
关键词：
GOLD NANOPARTICLE; ELECTRODE;
D O I：
10.1039/c5cc01975c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Combining the specific molecular recognition reaction between biotin and streptavidin with a dual-class signal amplification system, containing the unique optical properties of gold nanoparticles and the catalytic reaction of horseradish peroxidase, a double-enhanced strip biosensor was designed for the first time for a visual and rapid detection of protein biomarkers with good accuracy, especially for CEA with a detection limit of 2.9 fg mL(-1).
引用
收藏
页码：8273 / 8275
页数：3
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