Visceral adipose tissue had a causal, independent role in lowering the risk of Parkinson's disease: A mendelian randomization study

被引：3
|
作者：
Liu, Yaozhong [1 ]
Liu, Qiming [1 ]
机构：
[1] Cent South Univ, Xiangya Hosp 2, Dept Cardiovasc Med, 139 Middle Renmin Rd, Changsha 410011, Hunan, Peoples R China
来源：
PARKINSONISM & RELATED DISORDERS | 2021年 / 92卷
关键词：
Visceral adipose tissue; Mendelian randomization; Parkinson's disease; INSIGHTS;
D O I：
10.1016/j.parkreldis.2021.10.014
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Genetic evidence based on two-sample Mendelian randomization approaches suggested that visceral adipose tissue had a causal, independent role in lowering the risk of Parkinson's disease. Further studies are needed to explore the underlying mechanism.
引用
收藏
页码：51 / 52
页数：2
相关论文
共 50 条
  • [41] Examining the Causal Role of Leptin in Alzheimer Disease: A Mendelian Randomization Study
    Romo, Matthew L.
    Schooling, C. Mary
    [J]. NEUROENDOCRINOLOGY, 2017, 105 (02) : 182 - 188
  • [42] No Clear Support for a Role for Vitamin D in Parkinson's Disease: A Mendelian Randomization Study
    Larsson, Susanna C.
    Singleton, Andrew B.
    Nalls, Mike A.
    Richards, J. Brent
    [J]. MOVEMENT DISORDERS, 2017, 32 (08) : 1249 - 1252
  • [43] Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study
    Domenighetti, Cloe
    Sugier, Pierre-Emmanuel
    Sreelatha, Ashwin Ashok Kumar
    Schulte, Claudia
    Grover, Sandeep
    Mohamed, Oceane
    Portugal, Berta
    May, Patrick
    Bobbili, Dheeraj R.
    Radivojkov-Blagojevic, Milena
    Lichtner, Peter
    Singleton, Andrew B.
    Hernandez, Dena G.
    Edsall, Connor
    Mellick, George D.
    Zimprich, Alexander
    Pirker, Walter
    Rogaeva, Ekaterina
    Lang, Anthony E.
    Koks, Sulev
    Taba, Pille
    Lesage, Suzanne
    Brice, Alexis
    Corvol, Jean-Christophe
    Chartier-Harlin, Marie-Christine
    Mutez, Eugenie
    Brockmann, Kathrin
    Deutschlaender, Angela B.
    Hadjigeorgiou, Georges M.
    Dardiotis, Efthimos
    Stefanis, Leonidas
    Simitsi, Athina Maria
    Valente, Enza Maria
    Petrucci, Simona
    Duga, Stefano
    Straniero, Letizia
    Zecchinelli, Anna
    Pezzoli, Gianni
    Brighina, Laura
    Ferrarese, Carlo
    Annesi, Grazia
    Quattrone, Andrea
    Gagliardi, Monica
    Matsuo, Hirotaka
    Kawamura, Yusuke
    Hattori, Nobutaka
    Nishioka, Kenya
    Chung, Sun Ju
    Kim, Yun Joong
    Kolber, Pierre
    [J]. MOVEMENT DISORDERS, 2022, 37 (04) : 857 - 864
  • [44] Psoriasis and progression of Parkinson's disease: a Mendelian randomization study
    Li, C.
    Li, X.
    Lin, J.
    Cui, Y.
    Shang, H.
    [J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2022, 36 (12) : 2401 - 2405
  • [45] Protective effect of antihypertensive drugs on the risk of Parkinson's disease lacks causal evidence from mendelian randomization
    Jiang, Zheng
    Gu, Xiao-Jing
    Su, Wei-Ming
    Duan, Qing-Qing
    Ren, Yan-Lin
    Li, Ju-Rong
    Chi, Li-Yi
    Wang, Yi
    Cao, Bei
    Chen, Yong-Ping
    [J]. FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [46] Associations of Visceral Adipose Tissue, Circulating Protein Biomarkers, and Risk of Cardiovascular Diseases: A Mendelian Randomization Analysis
    Huang, Yunying
    Liu, Yaozhong
    Ma, Yingxu
    Tu, Tao
    Liu, Na
    Bai, Fan
    Xiao, Yichao
    Liu, Chan
    Hu, Zhengang
    Lin, Qiuzhen
    Li, Mohan
    Ning, Zuodong
    Zhou, Yong
    Mao, Xiquan
    Liu, Qiming
    [J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10
  • [47] Causal relationship between sleep disorders and the risk of Alzheimer's disease: A Mendelian randomization study
    Xiang, Wenwen
    Shen, Yu
    Chen, Shenjian
    Tan, Huadong
    Cao, Qian
    Xu, Lijun
    [J]. SLEEP MEDICINE, 2024, 120 : 34 - 43
  • [48] Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study
    Pichler, Irene
    Del Greco, Fabiola
    Goegele, Martin
    Lill, Christina M.
    Bertram, Lars
    Do, Chuong B.
    Eriksson, Nicholas
    Foroud, Tatiana
    Myers, Richard H.
    Nalls, Michael
    Keller, Margaux F.
    Benyamin, Beben
    Whitfield, John B.
    Pramstaller, Peter P.
    Hicks, Andrew A.
    Thompson, John R.
    Minelli, Cosetta
    [J]. PLOS MEDICINE, 2013, 10 (06)
  • [49] Lipid-lowering drug targets and Parkinson's disease: A sex-specific Mendelian randomization study
    Zhao, Yangfan
    Taliun, Sarah A. Gagliano A.
    [J]. FRONTIERS IN NEUROLOGY, 2022, 13
  • [50] Causal Relationship between Parkinson's Disease with Heart and Vascular Disease: A Two-Sample Mendelian Randomization Study
    Chen, Lize
    Zhang, Qiushi
    Li, Shiduo
    Chen, Haoran
    Guo, Jing
    Zhao, Zongmao
    Tong, Jing
    [J]. EUROPEAN NEUROLOGY, 2024, 87 (01) : 11 - 16
12345