Identification and Quantification of Chloramphenicol in Medicines by Multisensory Digital Colorimetry

An effective, affordable, and rapid method for the analysis of drugs based on chloramphenicol is developed using multisensory digital colorimetry. The use of a two-dimensional code for the identification and quantification of chloramphenicol with the minimum level of informational noise is proposed. The principal component analysis is used to increase the reliability of the results of the determination of the medicinal substance. The adequacy of the developed approach is confirmed by the analysis of chloramphenicol preparations in the form of two dosage forms: tablets and eye drops. The accuracy of the results is confirmed by the standard addition method. The results prove that the preparations do not have statistically significant differences from the values declared by the manufacturer.