Pedicle screw fixation combined with posterior decompression and bone grafting for thoracolumbar spinal fractures can enhance curative effect and spinal cord function

Objective: To explore the efficacy of pedicle screw fixation (PSF) combined with posterior decompression and bone grafting for thoracolumbar spinal fractures (TLSFs) and its influence on spinal cord function. Methods: In this retrospective study, 94 patients with TLSFs treated in the China-Japan Friendship Hospital rom June 2015 and September 2020 were selected, including 53 cases in the joint group treated with PSF combined with posterior decompression and bone grafting, and 41 cases in the control group with PSF alone. The two groups were compared in terms of operation time, intra-operational blood loss, length of hospital stay and wound healing as well as the pre- and post-treatment spinal cord function, and patients' clinical outcomes. Pre- and post-operatively, the pain severity was evaluated by the Visual Analogue Scale (VAS), the spinal dysfunction was assessed by Oswestry Disability Index (ODI), and the injured vertebral height and Cobb angles of the thoracolumbar spine (TLS) were compared. The clinical efficacy and postoperative complication rates of the two groups were observed and compared. Results: Less operative time, intraoperative bleeding, hospitalization time and wound healing time were determined in the joint group compared with the control group (all P<0.05). The postoperative sensory function and motor function were also better in the joint group (all P<0.05). Postoperatively, the joint group showed lower VAS and ODI scores than in the control group, with lower upper and lower TLS Cobb angles, and higher height of the anterior and posterior margins of the fractured vertebra (all P<0.05). The total effective rate was higher, and the incidence of postoperative complications was significantly lower in the joint group compared with the control group. Conclusion: PSF combined with posterior decompression and bone grafting is effective in the treatment of TLSFs, which can not only significantly improve the spinal cord function and alleviate spinal dysfunction, but also help to relieve pain and reduce postoperative complications.