The Role of Chromosomal Regions Anchored to the Nuclear Envelope in the Functional Organization of Chromosomes

被引：2
|
作者：
Shabarina, A. N. [1 ]
Shostak, N. G. [2 ]
Glazkov, M. V. [1 ]
机构：
[1] Russian Acad Sci, Koltsov Inst Dev Biol, Moscow 119334, Russia
[2] Russian Acad Sci, Engelhardt Inst Mol Biol, Moscow 119991, Russia
来源：
RUSSIAN JOURNAL OF GENETICS | 2010年 / 46卷 / 09期
关键词：
Nuclear Envelope; Site Specific Recombination; White Gene; Yellow Gene; Interphase Chromosome;
D O I：
10.1134/S1022795410090061
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The functional characteristics of the DNA fragments responsible for chromosome attachment to the nuclear envelope during the interphase (neDNAs) have been studied. The neDNAs flanking the transgene have been found to promote a steadily high rate of its expression, irrespective of the site of its insertion into the host chromosomes. At the same time, neDNAs themselves have no transcription regulatory functions.
引用
收藏
页码：1042 / 1044
页数：3
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