Sexual dimorphism and aromatase in the rat retina

被引：41
|
作者：
Salyer, DL
Lund, TD
Fleming, DE
Lephart, ED [1 ]
Horvath, TL
机构：
[1] Brigham Young Univ, Ctr Neurosci, Provo, UT 84602 USA
[2] Brigham Young Univ, Dept Psychol, Provo, UT 84602 USA
[3] Yale Univ, Sch Med, Dept Obstet & Gynecol, New Haven, CT 06520 USA
[4] Yale Univ, Sch Med, Neurobiol Sect, New Haven, CT 06520 USA
来源：
DEVELOPMENTAL BRAIN RESEARCH | 2001年 / 126卷 / 01期
关键词：
retinal thickness; aromatase; testosterone; flutamide; rat;
D O I：
10.1016/S0165-3806(00)00147-4
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The present study: (a) determined the effects of both pre- and early postnatal androgen hormonal manipulation on retinal thickness, (b) examined the presence of the aromatase enzyme by immunocytochemistry in retinal tissue and (c) quantified aromatase activity in the rat retina. The results suggest that retinal thickness is influenced by perinatal hormone manipulation via aromatizable androgens that have implications for the sex differences seen in visual information processing and performance. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：131 / 136
页数：6
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