Hypovitaminosis D as a risk factor of hip fracture severity

被引:37
|
作者
Larrosa, M. [1 ]
Gomez, A. [1 ]
Casado, E. [1 ]
Moreno, M. [1 ]
Vazquez, I. [1 ]
Orellana, C. [1 ]
Berlanga, E. [2 ]
Ramon, J. [3 ]
Gratacos, J. [1 ]
机构
[1] Univ Inst Parc Tauli UAB, Dept Rheumatol, Barcelona 08208, Spain
[2] Univ Inst Parc Tauli UAB, Lab UDIAT, Ctr Diagnost, Barcelona 08208, Spain
[3] Univ Inst Parc Tauli UAB, Dept Trauma & Orthopaed, Barcelona 08208, Spain
关键词
Functional status; Hip fracture; Hypovitaminosis D; Nutritional status; Osteoporosis; Parathyroid hormone; VITAMIN-D CONCENTRATIONS; FEMORAL-NECK FRACTURES; MORTALITY; MORBIDITY; CALCIUM;
D O I
10.1007/s00198-011-1588-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In a cross-sectional study including 324 patients older than 65 years admitted to our hospital for osteoporotic hip fracture, we found that those patients with a more severe vitamin D deficiency had more severe osteoporotic hip fractures (Garden grades III-IV and Kyle III-IV). To identify possible differences in baseline characteristics of patients with different types of osteoporotic hip fracture. Cross-sectional study including consecutive individuals over 65 admitted to our hospital for osteoporotic hip fracture over a year. Demographic data, fracture type, comorbidities, history of osteoporosis, functional capacity, nutritional status and vitamin D storage were evaluated. We included 324 patients (83 +/- 7 years, 80% women). Two hundred sixteen patients (67%) had vitamin D deficiency (25OHD3 < 25 ng/ml). In patients with severe femoral neck or intertrochanteric fractures (Garden III-IV and Kyle III-IV), vitamin D deficiency was more frequent (74%) and severe (25OHD3 20 +/- 15 ng/ml) than in patients with less severe fractures (57%, 25OHD3 26 +/- 21 ng/ml). Forty-three percent of patients had previous fractures. Only 15% of patients had been previously diagnosed with osteoporosis and 10% were receiving treatment. Patients receiving vitamin D supplements have higher 20OHD3 levels and less severe fractures. Although vitamin D levels are not different between patients with intracapsular or extracapsular hip fractures, a more severe vitamin D deficiency seems to be associated to more severe osteoporotic hip fractures. A prior vitamin D supplementation could avoid a higher severity of these fractures.
引用
收藏
页码:607 / 614
页数:8
相关论文
共 50 条
  • [21] OSTEOPOROSIS AND HIP FRACTURE: RISK FACTOR'S
    Sanchez-de las Matas, R.
    Fernandez-Garcia, G.
    OSTEOPOROSIS INTERNATIONAL, 2016, 27 : S547 - S548
  • [22] Prevalence of hypovitaminosis D and relationship to fracture
    Karen E. Hansen
    Nature Reviews Rheumatology, 2009, 5 : 417 - 418
  • [23] Reply to Barone et al.: Hypovitaminosis D and secondary hyperparathyroidism in the elderly: risk factors for hip fracture or markers of frailty?
    Sakuma, M.
    Endo, N.
    OSTEOPOROSIS INTERNATIONAL, 2007, 18 (11) : 1563 - 1563
  • [24] Severity of vertebral fracture and risk of hip fracture: a nested case–control study
    V. Puisto
    M. Heliövaara
    O. Impivaara
    T. Jalanko
    H. Kröger
    P. Knekt
    A. Aromaa
    H. Rissanen
    I. Helenius
    Osteoporosis International, 2011, 22 : 63 - 68
  • [25] Reply to Barone et al.: Hypovitaminosis D and secondary hyperparathyroidism in the elderly: risk factors for hip fracture or markers of frailty?
    M. Sakuma
    N. Endo
    Osteoporosis International, 2007, 18 : 1563 - 1563
  • [26] Prevalence of hypovitaminosis D and relationship to fracture
    Hansen, Karen E.
    NATURE REVIEWS RHEUMATOLOGY, 2009, 5 (08) : 417 - 418
  • [27] High prevalence of secondary hyperparathyroidism due to hypovitaminosis D in hospitalized elderly with and without hip fracture
    A. Giusti
    A. Barone
    M. Razzano
    M. Pizzonia
    M. Oliveri
    E. Palummeri
    G. Pioli
    Journal of Endocrinological Investigation, 2006, 29 : 809 - 813
  • [28] High prevalence of secondary hyperparathyroidism due to hypovitaminosis D in hospitalized elderly with and without hip fracture
    Giusti, A.
    Barone, A.
    Razzano, M.
    Pizzonia, M.
    Oliveri, M.
    Palummeri, E.
    Pioli, G.
    JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2006, 29 (09) : 809 - 813
  • [29] Hypovitaminosis D in the Greek Elderly Population Doesn't Concern Only Patients with Hip Fracture
    Papaioannou, Ioannis
    Pantazidou, Georgia
    Kostoglou-Athanasiou, Ifigeneia
    Korovessis, Panagiotis
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (08)
  • [30] IS HYPOALBUMINEMIA CORRELATED WITH HYPOVITAMINOSIS D IN ELDERLY WITH HIP FRACTURE WITH OR WITHOUT DIABETES MELLITUS TYPE 2?
    Papaioannou, I.
    Pantazidou, G.
    Repantis, T.
    Baikousis, A.
    Kokkalis, Z.
    Georgopoulos, N.
    Jelastopulu, E.
    AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2023, 35 : S278 - S279