Hypovitaminosis D as a risk factor of hip fracture severity

被引:37
|
作者
Larrosa, M. [1 ]
Gomez, A. [1 ]
Casado, E. [1 ]
Moreno, M. [1 ]
Vazquez, I. [1 ]
Orellana, C. [1 ]
Berlanga, E. [2 ]
Ramon, J. [3 ]
Gratacos, J. [1 ]
机构
[1] Univ Inst Parc Tauli UAB, Dept Rheumatol, Barcelona 08208, Spain
[2] Univ Inst Parc Tauli UAB, Lab UDIAT, Ctr Diagnost, Barcelona 08208, Spain
[3] Univ Inst Parc Tauli UAB, Dept Trauma & Orthopaed, Barcelona 08208, Spain
关键词
Functional status; Hip fracture; Hypovitaminosis D; Nutritional status; Osteoporosis; Parathyroid hormone; VITAMIN-D CONCENTRATIONS; FEMORAL-NECK FRACTURES; MORTALITY; MORBIDITY; CALCIUM;
D O I
10.1007/s00198-011-1588-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In a cross-sectional study including 324 patients older than 65 years admitted to our hospital for osteoporotic hip fracture, we found that those patients with a more severe vitamin D deficiency had more severe osteoporotic hip fractures (Garden grades III-IV and Kyle III-IV). To identify possible differences in baseline characteristics of patients with different types of osteoporotic hip fracture. Cross-sectional study including consecutive individuals over 65 admitted to our hospital for osteoporotic hip fracture over a year. Demographic data, fracture type, comorbidities, history of osteoporosis, functional capacity, nutritional status and vitamin D storage were evaluated. We included 324 patients (83 +/- 7 years, 80% women). Two hundred sixteen patients (67%) had vitamin D deficiency (25OHD3 < 25 ng/ml). In patients with severe femoral neck or intertrochanteric fractures (Garden III-IV and Kyle III-IV), vitamin D deficiency was more frequent (74%) and severe (25OHD3 20 +/- 15 ng/ml) than in patients with less severe fractures (57%, 25OHD3 26 +/- 21 ng/ml). Forty-three percent of patients had previous fractures. Only 15% of patients had been previously diagnosed with osteoporosis and 10% were receiving treatment. Patients receiving vitamin D supplements have higher 20OHD3 levels and less severe fractures. Although vitamin D levels are not different between patients with intracapsular or extracapsular hip fractures, a more severe vitamin D deficiency seems to be associated to more severe osteoporotic hip fractures. A prior vitamin D supplementation could avoid a higher severity of these fractures.
引用
收藏
页码:607 / 614
页数:8
相关论文
共 50 条
  • [1] Hypovitaminosis D as a risk factor of hip fracture severity
    M. Larrosa
    A. Gomez
    E. Casado
    M. Moreno
    I. Vázquez
    C. Orellana
    E. Berlanga
    J. Ramon
    J. Gratacos
    Osteoporosis International, 2012, 23 : 607 - 614
  • [2] HYPOVITAMINOSIS D AS A RISK FACTOR OF HIP FRACTURE SEVERITY IN A SUNNY MEDITERRANEAN REGION
    Papaioannou, I.
    Pantazidou, G.
    Baikousis, A.
    Kostoglou-Athanassiou, I.
    Korovessis, P.
    OSTEOPOROSIS INTERNATIONAL, 2020, 31 (SUPPL 1) : S266 - S266
  • [3] Hypovitaminosis D in hip fracture patients.
    Miura, L. N.
    White-Chu, F.
    Homer, L.
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2007, 55 (04) : S194 - S194
  • [4] Hypovitaminosis D in hip fracture patients.
    Miura, L. N.
    White-Chu, E. F.
    Haney, E. M.
    Homer, L.
    JOURNAL OF GENERAL INTERNAL MEDICINE, 2006, 21 : 68 - 68
  • [5] Hypovitaminosis D and secondary hyperparathyroidism in the elderly: risk factors for hip fracture or markers of frailty?
    Barone, A.
    Giusti, A.
    Pioli, G.
    OSTEOPOROSIS INTERNATIONAL, 2007, 18 (11) : 1561 - 1562
  • [6] Hypovitaminosis D and secondary hyperparathyroidism in the elderly: risk factors for hip fracture or markers of frailty?
    A. Barone
    A. Giusti
    G. Pioli
    Osteoporosis International, 2007, 18 : 1561 - 1562
  • [7] The incidence of hypovitaminosis-D in hip fracture, a retrospective study
    Meals, Clifton
    Benke, Michael
    Neviaser, Robert
    O'Brien, Joseph
    CURRENT ORTHOPAEDIC PRACTICE, 2012, 23 (06): : 572 - 576
  • [8] High prevalence of hypovitaminosis D and K in patients with hip fracture
    Nakano, Tetsuo
    Tsugawa, Naoko
    Kuwabara, Akiko
    Kamao, Maya
    Tanaka, Kiyoshi
    Okano, Toshio
    ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION, 2011, 20 (01) : 56 - 61
  • [9] Do risk factors for hip fracture vary by the severity of the hip fracture?
    Cauley, J.
    Lui, L.
    Genant, H. K.
    Browner, W.
    Fink, H.
    Cohen, P.
    Hillier, T.
    Bauer, D.
    Cummings, S. R.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 : S7 - S7
  • [10] Hypovitaminosis D-Risk factor for endometriosis
    Vatakencherry, Jacob R. M.
    Saraswathy, L.
    Radhamany, K.
    Krishnan, S.
    Sundaram, K. R.
    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2014, 121 : 61 - 61