Variation in the Quantity of Elastic Fibres with Degeneration in Canine Cranial Cruciate Ligaments from Labrador Retrievers

被引：0
|
作者：
Smith, Kinley D. [1 ]
Hayashi, Kei [5 ]
Clements, Dylan N. [3 ,4 ]
Clegg, Peter D. [2 ]
Innes, John F. [6 ]
Comerford, Eithne J. [2 ]
机构：
[1] Willows Vet Ctr & Referral Serv, Solihull, W Midlands, England
[2] Univ Liverpool, Dept Musculoskeletal Biol, Inst Aging & Chron Dis, Fac Hlth & Life Sci, Liverpool, Merseyside, England
[3] Univ Edinburgh, Div Clin Vet Sci, Royal Dick Sch Vet Studies, Edinburgh, Midlothian, Scotland
[4] Univ Edinburgh, Roslin Inst, Edinburgh, Midlothian, Scotland
[5] Cornell Univ, Coll Vet Med, Dept Clin Sci, Ithaca, NY 14853 USA
[6] ChesterGates Vet Specialists, Gates Rd, Chester CH1 6LT, Cheshire, England
来源：
VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY | 2017年 / 30卷 / 06期
基金：
英国生物技术与生命科学研究理事会;
关键词：
dogs; cruciate ligament disease; elastic fibres; PERIODONTAL-LIGAMENT; OXYTALAN FIBERS; KNEE-JOINT; DOGS; RUPTURE; DISEASE; PREDISPOSITION; REPAIR; SCAR;
D O I：
10.3415/VCOT-17-02-0019
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Objectives This study aims to quantify numbers of elastic fibres in cranial cruciate ligaments from a dog breed at high risk of cranial cruciate ligament disease. Methods Macroscopically normal cranial cruciate ligaments were harvested from six Labrador retrievers. Sequential histological sections were assessed for extracellular matrix degeneration (haematoxylin and eosin stain) and elastic fibre staining (Miller's stain). Elastic fibres were semi-quantified using previously published scoring systems. Each section was scored twice by two observers. Results Increased numbers of elastic fibres were seen with increasing cranial cruciate ligament degeneration (p = .001). Labrador retriever cranial cruciate ligaments had lower elastic fibre staining when compared with previous published findings in the racing greyhound. Clinical Significance The cranial cruciate ligaments from a dog breed at high risk of cranial cruciate ligament disease vary in the quantity of elastic fibres in association with ligament degeneration. Breed variation in the quantity of elastic fibres may reflect differing risk of cranial cruciate ligament disease.
引用
收藏
页码：398 / 402
页数：5
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