Covid-19: current knowledge, disease potential, prevention and clinical advances

被引:7
|
作者
Alam, Aftab [1 ]
Siddiqui, Mohd Faizan [2 ]
Imam, Nikhat [3 ]
Ali, Rafat [1 ]
Mushtaque, Md [4 ]
Ishrat, Romana [1 ]
机构
[1] JMI Univ, Ctr Interdisciplinary Res Basic Sci, New Delhi, India
[2] Osh State Univ, Int Med Fac, Osh City, Kyrgyz Republic, Kyrgyzstan
[3] Magadh Univ, Inst Comp Sci & Informat Technol, Dept Math, Bodh Gaya, Bihar, India
[4] Al Falah Univ, Sch Phys & Mol Sci, Dept Chem, Faridabad, Haryana, India
关键词
COVID-19; transmission rate (Ro); mortality rate; vaccines; antivirals; financial crisis; EAST RESPIRATORY SYNDROME; SYNDROME CORONAVIRUS; MYCOPHENOLIC-ACID; INTERFERON-BETA; INHIBITORS; INFECTION; MERS; SARS; GRIFFITHSIN; COMBINATION;
D O I
10.3906/biy-2005-29
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The top priority of any nation is to lead the nation towards prosperity, progress, and economic growth, confronting several challenges and concerns arisen from global situations. The sudden outbreak of any disease defies the health care systems and economy of nations. COVID-19 is one of the viral diseases which broke out in Wuhan city of China in 2019. COVID-19 outbreak intermittently prevailed all over the world. It exposes the fragility of the established health care systems across the world in spite of comprising modern science and technology. Unfortunately, there is no chemotherapeutic agent in the regimen of antiviral drugs or no vaccine available to curb this infectious disease. As a consequence, this deadly infection has prevailed all over the world. The antiviral drugs used for viral diseases excluding COVID-19 infection are Ramdesvir, Favipiravir, and Ribavarin, and antimalarial agents (Chloroquine & Hydroxychloroquine) are being administered to the patients for redemption of this infection. Fortunately, these existing drugs have been found clinically active and are being used. In this review, we present the current scenario and status of epidemiology, diagnosis, treatment, vaccine development for COVID-19, and its impact on the socio-economic structure.
引用
收藏
页码:121 / 131
页数:11
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