Monoclonal gammopathy of undetermined significance and multiple myeloma

被引：2

作者：

Schmalzing, M. ^{[1
]}

Tony, H. -P. ^{[1
]}

Knop, S. ^{[1
]}

机构：

[1] Univ Klinikum Wurzburg, Med Klin & Poliklin 2, Oberdurrbacher Str 6, D-97080 Wurzburg, Germany

来源：

ZEITSCHRIFT FUR RHEUMATOLOGIE | 2017年 / 76卷

关键词：

RHEUMATOID-ARTHRITIS; PSORIATIC PATIENTS; THERAPY; DEXAMETHASONE; RISK;

D O I：

10.1007/s00393-017-0335-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In rheumatological practice monoclonal gammopathy of undetermined significance (MGUS) is a common incidental finding. Several rheumatic inflammatory diseases are known to have an elevated risk of MGUS, which can evolve into multiple myeloma or other lymphatic malignancies. The relevant definitions of disease entities are described, as well as algorithms for further diagnostic work-up and follow-up for monoclonal gammopathy, depending on the risk of progression. Therapeutic strategies against multiple myeloma are presented. Some of these therapeutic modalities could play a future role in treating plasma cell-dominated autoimmune diseases.

引用

页码：33 / 37

页数：5

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