Selective PRMT5 inhibition suppresses inflammatory T cell responses and autoimmunity.

被引:0
|
作者
Webb, Lindsay M.
Savardekar, Himanshu
Jablonski, Kyle A.
Amici, Stephanie A.
Panfil, Amanda
Li, Linsen
Green, Patrick L.
Li, Chenglong
Baiocchi, Robert A.
Guerau-De-Arellano, Mireia
机构
来源
JOURNAL OF IMMUNOLOGY | 2017年 / 198卷 / 01期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
156.12
引用
收藏
页数:4
相关论文
共 50 条
  • [41] Selective, novel, small molecule PRMT5 inhibitors for treatment of cancer.
    Sivanandhan, Dhanalakshmi
    Rajagopal, Sridharan
    Sadhu, Naveen M.
    Gajendran, Chandru
    Vadivelu, Saravanan
    Tamizharasan, Natarajan
    Swamy, Indu N.
    Viswakarma, Santhosh
    Siddiqui, Amir
    wahid, Saif
    Zainuddin, Mohammed
    Rudresh, G.
    Daram, Prashanthi
    Gosu, Ramchandraiah
    Tiagaraj, Dinesh
    Garapaty, Shivani
    Nair, Sreekala
    Kapoor, Namratha
    CANCER RESEARCH, 2021, 81 (13)
  • [42] Sulforaphane suppression of Prmt5 and Mep50 function suppresses the mesothelioma cancer stem cell phenotype.
    Ezeka, Geraldine C.
    Adhikary, Gautam
    Kandasamy, Sivaveera
    Friedberg, Joseph
    Eckert, Richard
    CANCER RESEARCH, 2021, 81 (13)
  • [43] PRMT5 Inhibition Reduces Autoinflammation in a Murine Model of Secondary Hemophagocytic Lymphohistiocytosis
    Shindiapina, Polina
    Saadey, Rachel
    Yasin, Aneeq
    Mao, Charlene
    Wandke, Alexa
    Ahmed, Elshafa Hassan
    Baiocchi, Ethan
    Vaddi, Kris
    Scherle, Peggy
    Brown, Fiona
    Mozhenkova, Anna
    El Ayachi, Ikbale
    Schenk, Austin D.
    Sloan, Shelby
    Harrison, Kaylee
    Helmig-Mason, JoBeth
    Baiocchi, Robert A.
    BLOOD, 2022, 140
  • [44] Protein Arginine Methyltransferase 5 (PRMT5) and the ERK1/2 & PI3K Pathways: A Case for PRMT5 Inhibition and Combination Therapies in Cancer
    Sapir, Tzuriel
    Shifteh, David
    Pahmer, Moshe
    Goel, Sanjay
    Maitra, Radhashree
    MOLECULAR CANCER RESEARCH, 2021, 19 (03) : 388 - 394
  • [45] PRMT5 Inhibition Affects RNA Methylation and Is a Potential Therapeutic Target in BPDCN
    Rethnam, Malini
    Tan, Darren Qiancheng
    Tan, Shi Hao
    Ying, Li
    Yang, Henry
    Suda, Toshio
    BLOOD, 2020, 136
  • [46] Prmt5 is a regulator of muscle stem cell expansion in adult mice
    Zhang, Ting
    Guenther, Stefan
    Looso, Mario
    Kuenne, Carsten
    Krueger, Marcus
    Kim, Johnny
    Zhou, Yonggang
    Braun, Thomas
    NATURE COMMUNICATIONS, 2015, 6
  • [47] PRMT5 regulates B cell development and germinal center homeostasis
    Litzler, L. C.
    Zahn, A.
    Methot, S. P.
    Bois, T.
    Richard, S.
    Di Noia, J. M.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 46 : 1071 - 1071
  • [48] PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma
    Sloan, Shelby L.
    Brown, Fiona
    Long, Mackenzie
    Weigel, Christoph
    Koirala, Shirsha
    Chung, Ji-Hyun
    Pray, Betsy
    Villagomez, Lynda
    Hinterschied, Claire
    Sircar, Anuvrat
    Helmig-Mason, Jobeth
    Prouty, Alexander
    Brooks, Eric
    Youssef, Youssef
    Hanel, Walter
    Parekh, Samir
    Chan, Wing Keung
    Chen, Zhengming
    Lapalombella, Rosa
    Sehgal, Lalit
    Vaddi, Kris
    Scherle, Peggy
    Chen-Kiang, Selina
    Di Liberto, Maurizio
    Elemento, Olivier
    Meydan, Cem
    Foox, Jonathan
    Butler, Daniel
    Mason, Christopher E.
    Baiocchi, Robert A.
    Alinari, Lapo
    BLOOD, 2023, 142 (10) : 887 - 902
  • [49] PRMT5 is Required for Human Embryonic Stem Cell Proliferation But Not Pluripotency
    Sofia Gkountela
    Ziwei Li
    Chee Jia Chin
    Serena A. Lee
    Amander T. Clark
    Stem Cell Reviews and Reports, 2014, 10 : 230 - 239
  • [50] PRMT5 is Required for Human Embryonic Stem Cell Proliferation But Not Pluripotency
    Gkountela, Sofia
    Li, Ziwei
    Chin, Chee Jia
    Lee, Serena A.
    Clark, Amander T.
    STEM CELL REVIEWS AND REPORTS, 2014, 10 (02) : 230 - 239