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Weight and body mass index in Parkinson's disease patients after deep brain stimulation surgery
被引:51
|作者:
Tuite, PJ
Maxwell, RE
Ikramuddin, S
Kotzd, CM
Billingtond, CJ
Laseski, MA
Thielen, SD
机构:
[1] Fairview Univ, Med Ctr, Dept Neurol, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Minneapolis, MN 55455 USA
[3] Fairview Univ, Med Ctr, Dept Neurosurg, Minneapolis, MN 55455 USA
[4] Fairview Univ, Med Ctr, Dept Surg, Minneapolis, MN 55455 USA
[5] Vet Affairs Med Ctr, Minneapolis, MN USA
[6] Minnesota Obes Ctr, Minneapolis, MN USA
[7] Univ Minnesota, Dept Food Sci & Nutr, St Paul, MN 55108 USA
[8] Univ Minnesota, Dept Food Sci & Nutr, Minneapolis, MN 55455 USA
[9] Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA
[10] Univ Minnesota, Dept Med, St Paul, MN 55108 USA
关键词:
Parkinson's disease;
deep brain stimulation;
weight;
obesity;
D O I:
10.1016/j.parkreldis.2005.01.006
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
A retrospective chart review characterizing changes in 17 male and 10 female Parkinson's disease (PD) patients undergoing deep brain stimulation (DBS) surgery indicated that 6 mo before surgery, patients lost a mean of 5.1 lbs, whereas in the 6 mo after surgery, subjects gained a mean of 10.1 lbs; 22% gained more than 14 lbs. In 10 patients followed an additional 6 mo, weight gain continued. This weight gain may be associated with decreased energy expenditure due to subsidence of chronic tremor. The magnitude of gain underscores the need for proactive management of body weight in PD patients undergoing DBS. (c) 2005 Elsevier Ltd. All rights reserved.
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页码:247 / 252
页数:6
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