One-pot transformation of cyano oxiranes into furo[3,2-c]isothiazole derivatives

被引：10
|
作者：
Bardasov, Ivan N. [1 ]
Golubev, Roman V. [1 ]
Ershov, Oleg V. [1 ]
Kayukov, Yakov S. [1 ]
Nasakin, Oleg E. [1 ]
机构：
[1] Ulyanov Chuvash State Univ, Cheboksary, Russia
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 37期
关键词：
Heterocyclic compounds; Cyano compounds; Oxiranes; Isothiazoles; Furans; One-pot synthesis; ORGANIC-CHEMISTRY; BIOLOGICAL-ACTIVITY; MALONONITRILE; TETRACYANOETHYLENE; NITRILES; BIS(TRIMETHYLSILYL)SULFIDE; CYANOACETATE; ROUTE;
D O I：
10.1016/j.tetlet.2011.06.083
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one-pot reactions of 2-[amino(2-cyano-3-aryloxiran-2-yl)methylene]malononitriles with thiocyanate to afford 5-amino-3-arylfurol[3,2-c]isothiazole-6-carbonitriles in good yields. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4724 / 4725
页数：2
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