Monoamine oxidase-A gene promoter polymorphism in female migraineurs

被引：1
|
作者：
Erdal, ME
Herken, H
Yilmaz, M
Bayazit, YA [1 ]
机构：
[1] Mersin Univ, Fac Med, Dept Med Biol & Genet, Mersin, Turkey
[2] Univ Gaziantep, Fac Med, Dept Psychiat, Gaziantep, Turkey
[3] Univ Gaziantep, Fac Med, Dept Neurol, Gaziantep, Turkey
[4] Univ Gaziantep, Fac Med, Dept Otolaryngol, Gaziantep, Turkey
来源：
PAIN CLINIC | 2003年 / 15卷 / 04期
关键词：
monoarnine oxidase gene; polymorphism; migraine; aura;
D O I：
10.1163/156856903770196854
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: To assess whether there is a relationship between monoamine oxidase, A (MAOA) gene promoter polymorphism and migraine in female patients. Study design: A polymerase chain reaction based study in which MAOA promoter polymorphism was studied in 54 female migraineurs and 52 controls. Methods: The low (3-repeat) and high (one of 3.5, 4 or 5 repeat units) activity MAOA alleles were detected. The genotypes and allele frequencies were compared both within and between the groups. Results: The representation of both low (1/1) and high (2/2) activity genotypes were similar between the female migraineurs and controls. The allele frequencies were also similar between these groups. There was no relationship between the presence or absence of aura and MAO polymorphism. Conclusion: MAOA gene polymorphism is not associated with migraine or aura in female patients.
引用
收藏
页码：455 / 458
页数：4
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