Nonopioid versus opioid agents for chronic neuropathic pain, rheumatoid arthritis pain, cancer pain and low back pain

被引:24
|
作者
Noori, Selaiman A. [1 ]
Aiyer, Rohit [2 ]
Yu, James [3 ]
White, Robert S. [2 ]
Mehta, Neel [2 ]
Gulati, Amitabh [4 ]
机构
[1] Cleveland Clin, Dept Pain Management, Anesthesiol Inst, Cleveland, OH 44195 USA
[2] NewYork Presbyterian Hosp, Dept Anesthesiol, Weill Cornell Med, New York, NY 10065 USA
[3] Univ Illinois, Dept Anesthesiol, Coll Med, Chicago, IL 60612 USA
[4] Mem Sloan Kettering Canc Ctr, Dept Anesthesia & Crit Care, New York, NY 10065 USA
关键词
cancer pain; inflammatory pain; low back pain; neuropathic pain; opioids; rheumatologic pain; UNITED-STATES; TREAT;
D O I
10.2217/pmt-2018-0052
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Chronic pain continues to be a major health issue throughout the world and a huge economic burden for nations around the world. While the use of opioids does have risks, they are still widely used by clinicians as a treatment option for various chronic pain conditions. This review explores and compares the efficacy and safety of opioid and nonopioid agents for the following commonly encountered chronic pain conditions: neuropathic pain, rheumatoid arthritis joint pain, cancer pain and low back pain. Our findings demonstrate that while there are several nonopioid pharmacologic options that are clinically effective, opioids maintain a role in the treatment of certain chronic pain conditions and should continue to have an important place in the armamentarium of clinicians.
引用
收藏
页码:205 / 216
页数:12
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