Ultrasonic-Assisted Extraction of Puerarin Optimized by Response Surface Methodology

Extraction of puerarin by ultrasound, optimization requires to determine the technological parameters. In this paper, ultrasonic parameter is one of the technological parameters. The ethanol volume ratio, the intensity of cavitation ultrasonic power, and liquid-solid ratio were optimized by response surface methodology. Modeling the optimization of technological parameters by Design-expert software, thereby obtaining the global optimal parameters, three independent variables were the ethanol volume ratio (A: 68 %), the liquid-solid ratio (B: 53:1), and the intensity of cavitation power ultrasonic (5:1). Under these conditions, extraction rate of puerarin was 7.09 %. The result shows that taking ultrasonic parameters as optimized parameters, and optimizing ultrasonic-assisted extraction of puerarin by response surface methodology could get better performance.