The Participation of Cytochrome P450 3A4 in Clozapine Biotransformation Is Detected in People With Schizophrenia by High-Throughput In Vivo Phenotyping

被引:5
|
作者
Ghassabian, Sussan [1 ]
Chetty, Manoranjenni [1 ]
Tattam, Bruce N. [1 ]
Glen, John [2 ]
Rahme, Jeannie [2 ]
Stankovic, Zvijezdana [2 ]
Ramzan, Iqbal [1 ]
Murray, Michael [1 ]
McLachlan, Andrew J. [1 ,3 ]
机构
[1] Univ Sydney, Fac Pharm, Camperdown, NSW, Australia
[2] Macquarie Hosp, N Ryde, NSW, Australia
[3] Concord Hosp, Ctr Educ & Res Ageing, Concord, NSW, Australia
关键词
CYP1A2; ACTIVITY; METABOLISM; ISOFORMS;
D O I
10.1097/JCP.0b013e3181f03e30
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:629 / 631
页数:3
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