Hydroxyl radical is predominantly involved in oxidatively generated base damage to cellular DNA exposed to ionizing radiation

被引：12
|
作者：
Cadet, Jean [1 ]
Angelov, Dimitar [2 ,3 ]
Wagner, J. Richard [1 ]
机构：
[1] Univ Sherbrooke, Fac Med, Dept Med Nucl & Radiobiol, Sherbrooke, PQ, Canada
[2] Univ Lyon, CNRS, Ecole Normale Super Lyon, Lab Biol & Modelisat Cellule LBMC, Lyon, France
[3] Dokuz Eylul Univ Hlth Campus, Izmir Biomed & Genome Ctr IBG, Izmir, Turkey
来源：
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY | 2022年 / 98卷 / 11期
基金：
加拿大自然科学与工程研究理事会;
关键词：
ONE-ELECTRON OXIDATION; UV LASER PHOTOLYSIS; B GENE-PRODUCT; HO-CENTER-DOT; GAMMA-RADIATION; TRANSFORMATION REACTIONS; DUPLEX STABILITY; AQUEOUS-SOLUTION; MAMMALIAN-CELLS; EXCISION-REPAIR;
D O I：
10.1080/09553002.2022.2067363
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
[No abstract available]
引用
收藏
页码：1684 / 1690
页数：7
相关论文
共 50 条
  • [31] RADICAL YIELDS IN DNA EXPOSED TO IONIZING-RADIATION - ROLE OF ENERGY AND CHARGE-TRANSFER
    MILLER, JH
    SWENBERG, CE
    CANADIAN JOURNAL OF PHYSICS, 1990, 68 (09) : 962 - 966
  • [32] Furfural, a precursor of the cytokinin hormone kinetin, and base propenals are formed by hydroxyl radical damage of DNA
    Barciszewski, J
    Siboska, GE
    Pedersen, BO
    Clark, BFC
    Rattan, SIS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 238 (02) : 317 - 319
  • [33] Ionizing Radiation-Induced Cellular Senescence in Normal, Non-transformed Cells and the Involved DNA Damage Response: A Mini Review
    Li, Mengqian
    You, Liting
    Xue, Jianxin
    Lu, You
    FRONTIERS IN PHARMACOLOGY, 2018, 9
  • [34] Chromosome length ratio as a biomarker of DNA damage in cells exposed to high dose ionizing radiation
    Meenakshi, C.
    Venkatachalam, P.
    Srinivas, K. Satish
    Chandrasekaran, S.
    Venkatraman, B.
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2022, 879-880
  • [35] MODELS FOR DNA DAMAGE FORMATION AND REPAIR IN MAMMALIAN-CELLS EXPOSED TO IONIZING-RADIATION
    NELSON, SJ
    RADIATION RESEARCH, 1982, 92 (01) : 120 - 145
  • [36] DNA-DAMAGE PRODUCED BY EXPOSURE OF SUPERCOILED PLASMID DNA TO HIGH-LET AND LOW-LET IONIZING-RADIATION - EFFECTS OF HYDROXYL RADICAL QUENCHERS
    PEAK, JG
    ITO, T
    ROBB, FT
    PEAK, MJ
    INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1995, 67 (01) : 1 - 6
  • [37] Survival, DNA Integrity, and Ultrastructural Damage in Antarctic Cryptoendolithic Eukaryotic Microorganisms Exposed to Ionizing Radiation
    Pacelli, Claudia
    Selbmann, Laura
    Zucconi, Laura
    Raguse, Marina
    Moeller, Ralf
    Shuryak, Igor
    Onofri, Silvano
    ASTROBIOLOGY, 2017, 17 (02) : 126 - 135
  • [38] REPAIR OF IONIZING-RADIATION DNA-BASE DAMAGE IN ATAXIA-TELANGIECTASIA CELLS
    FORNACE, AJ
    KINSELLA, TJ
    DOBSON, PP
    MITCHELL, JB
    CANCER RESEARCH, 1986, 46 (04) : 1703 - 1706
  • [39] The effects of thymoquinone on DNA damage, apoptosis and oxidative stress in an osteoblast cell line exposed to ionizing radiation
    Yilmaz, Osman
    Yuksek, Veysel
    Cetin, Sedat
    Dede, Semiha
    Tugrul, Taylan
    RADIATION EFFECTS AND DEFECTS IN SOLIDS, 2021, 176 (5-6): : 575 - 589
  • [40] Activation of eNOS in endothelial cells exposed to ionizing radiation involves components of the DNA damage response pathway
    Nagane, Masaki
    Yasui, Hironobu
    Sakai, Yuri
    Yamamori, Tohru
    Niwa, Koichi
    Hattori, Yuichi
    Kondo, Takashi
    Inanami, Osamu
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 456 (01) : 541 - 546
12345