The interplay between the intestinal microbiota and the immune system

被引：61

作者：

Lei, Yuk Man Kevin ^{[1
]}

Nair, Lekha ^{[1
]}

Alegre, Maria-Luisa ^{[1
]}

机构：

[1] Univ Chicago, Dept Med, Rheumatol Sect, Chicago, IL 60637 USA

来源：

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY | 2015年 / 39卷 / 01期

关键词：

SEGMENTED FILAMENTOUS BACTERIA; INNATE LYMPHOID-CELLS; ARYL-HYDROCARBON RECEPTOR; REGULATORY T-CELLS; COMMENSAL BACTERIA; DENDRITIC CELLS; GUT MICROBIOME; SYMBIOTIC BACTERIA; ORAL TOLERANCE; T(H)17 CELLS;

D O I：

10.1016/j.clinre.2014.10.008

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The relationship between commensal microbes and their hosts has been studied for many years. Commensal microorganisms are known to have a significant role in regulating the physiology of their hosts and preventing pathogenic infections while the hosts' immune system is important in determining the composition of the microbiota. More recently, specific effects of the intestinal microbiota on the local and distal immune systems have been uncovered with important consequences for health and disease, and alterations in intestinal microbial composition has been associated with various disease states. Here, we will review the current understanding of the microbiota/immune system crosstalk, highlight the clinical consequences of changes in the microbiota and consider how to harness this symbiotic relationship to improve public health. (C) 2014 Elsevier Masson SAS. All rights reserved.

引用

页码：9 / 19

页数：11

共 50 条

[21] Butterflies in the gut: the interplay between intestinal microbiota and stress
Tzu-Ting Lai
Chia-Wei Liou
Yu-Hsuan Tsai
Yuan-Yuan Lin
Wei-Li Wu
[J]. Journal of Biomedical Science, 30
[22] Role of microRNAs in the crosstalk between the gut microbiota and intestinal immune system
Sonoyama, Kei
Ohsaka, Fumina
[J]. BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH, 2023, 42 (04) : 222 - 228
[23] The intestinal virobiota, a new component in the interactions between the microbiota and the immune system
Henrot, Caroline
Kuksin, Maria
[J]. M S-MEDECINE SCIENCES, 2019, 35 (6-7): : 578 - 580
[24] Secretory IgA: an actor of the interplay between the commensal flora and the intestinal immune system?
Rol, N.
Corthesy, B.
[J]. ALLERGOLOGIE, 2011, 34 (02) : 100 - 100
[25] Editorial: Interplay between oncomicrobes, the microbiota and the immune system: impact on responses to cancer immunotherapy
Dorta-Estremera, Stephanie M.
Peterson, Esther A.
Perez-Santiago, Josue
Sekiguchi, JoAnn M.
[J]. FRONTIERS IN IMMUNOLOGY, 2023, 14
[26] Editorial: Interplay between gut microbiota and the immune system in liver surgery and liver diseases
Plaza-Diaz, Julio
Fontana, Luis
Alvarez-Mercado, Ana, I
[J]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2023, 13
[27] Interplay Between Skin Microbiota Dysbiosis and the Host Immune System in Psoriasis: Potential Pathogenesis
Liang, Xiaoqian
Ou, Caixin
Zhuang, Jiayi
Li, Jinsheng
Zhang, Fangfei
Zhong, Yuanqiu
Chen, Yongfeng
[J]. FRONTIERS IN IMMUNOLOGY, 2021, 12
[28] Complex interplay between the immune system and the infant gut microbiota: Potential health implications
Jenmalm, Maria
[J]. TOXICOLOGY LETTERS, 2016, 258 : S17 - S17
[29] Crosstalk Between the Intestinal Microbiota and the Innate Immune System in Intestinal Homeostasis and Inflammatory Bowel Disease
Dupaul-Chicoine, Jeremy
Dagenais, Maryse
Saleh, Maya
[J]. INFLAMMATORY BOWEL DISEASES, 2013, 19 (10) : 2227 - 2237
[30] The functional interplay between the intestinal microbiota, T cells, and immunoglobulins
Koegler, M.
Burkhard, R.
Geuking, M.
[J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 1328 - 1329

← 1 2 3 4 5 →