A genetic characterization of differences in the sensitivity to radiation-induced malformation frequencies in the mouse strains Heiligenberger, C57BI, and Heiligenberger x C57BI

被引：6
|
作者：
Muller, WU
Streffer, C
Knoelker, M
机构：
来源：
RADIATION AND ENVIRONMENTAL BIOPHYSICS | 1996年 / 35卷 / 01期
关键词：
D O I：
10.1007/BF01211241
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We studied the frequency of malformations induced in two mouse strains (Heiligenberger, C57B1/6J) by exposure to x-rays 3 h after conception. Whereas there was a high number of malformed fetuses in Heiligenberger mice (mostly gastroschises) on day 19 of pregnancy, C57B1 did not respond to radiation exposure shortly after conception with an increased frequency of malformed fetuses. Cross-breeding of both strains revealed that no statistically significant increase in radiation-induced malformations was obtained in the F-1 fetuses when the father was Heiligenberger and the mother C57B1, In the opposite case (Heibligenberger mother, C57B1 father) a small but statistically significant increase was observed.
引用
收藏
页码：37 / 40
页数：4
相关论文
共 50 条
  • [41] Periadventitial Adipose Tissue Promotes Endothelial Dysfunction via Oxidative Stress in Diet-Induced Obese C57BI/6 Mice
    Ketonen, Juha
    Shi, Jin
    Martonen, Essi
    Mervaala, Eero
    CIRCULATION JOURNAL, 2010, 74 (07) : 1479 - 1487
  • [42] Expression profiling of spleen leukocytes reveal strain-specific patterns in NOD, NON and C57BI/6 mice
    Gerling, IC
    Wu, J
    Marshall, DR
    Lenchik, N
    DIABETES, 2004, 53 : A265 - A265
  • [43] Circulating tumour necrosis factor α is not involved in the development of cerebral malaria in Plasmodium berghei-infected C57BI mice
    Hermsen, CC
    Crommert, JVD
    Fredrix, H
    Sauerwein, RW
    Eling, WMC
    PARASITE IMMUNOLOGY, 1997, 19 (12) : 571 - 577
  • [44] Effects of Short-Term Administration of Delta-9-tetrahydrocannabinol on Metabolic Parameters of C57bI/16 Mice
    Kurjan, Emily
    Olson, Lawrence K.
    Alshaarawy, Omayma
    DIABETES, 2021, 70
  • [45] INVITRO STUDIES OF THE DEVELOPMENT OF PITUITARY AND TESTICULAR FUNCTIONS IN DIABETES (C57BI/KSJ-DB/DB) MUTANT MICE
    KUHNVELTEN, N
    CODJAMBOPOULO, P
    HERBERG, L
    KLEY, HK
    STAIB, W
    HORMONE AND METABOLIC RESEARCH, 1985, 17 (11) : 576 - 579
  • [46] CIRCADIAN VARIATIONS OF NORADRENALINE, 5-HYDROXYTRYPTAMINE AND DOPAMINE IN SPECIFIC BRAIN-AREAS OF C57BI/6 AND BALB/C MICE
    KEMPF, E
    MANDEL, P
    OLIVERIO, A
    PUGLISIALLEGRA, S
    BRAIN RESEARCH, 1982, 232 (02) : 472 - 478
  • [47] Chemokine and antioxidant mRNA expression after acute ozone and nitrogen dioxide exposures in C57BI/6 mice.
    Finkelstein, JN
    Johnston, CJ
    Reed, CK
    Avissar, NE
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (03) : A491 - A491
  • [48] PLASMODIUM BERGHEI-INFECTION IN ISOGENIC F1(C57BI X DBA)-MICE .2. ANTIBODIES AND ANTIGENS IN SERUM
    SEITZ, HM
    TROPENMEDIZIN UND PARASITOLOGIE, 1976, 27 (01): : 33 - 43
  • [49] Effect of high-frequency low-intensity irradiation on reproductive function in C57BI/6 and randombred mice
    Subbotina, TI
    Khadartsev, AA
    Yashin, MA
    Yashin, AA
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2004, 138 (06) : 554 - 555
  • [50] Preferential distribution of NK cells into uteri of C57BI/6J mice after adoptive transfer of lymphocytes
    Wu, Dongmei
    Zhang, Hanhong
    Sun, Rui
    Wei, Haiming
    Tian, Zhigang
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2007, 75 (02) : 120 - 127
12345