Stem cell transplantation for type 1 diabetes mellitus

被引:0
|
作者
Voltarelli, Julio C. [1 ]
Barra Couri, Carlos Eduardo [1 ]
机构
[1] Univ Sao Paulo, Ribeirao Preto Sch Med, Dept Clin Med, BR-05508 Sao Paulo, Brazil
来源
关键词
Systemic Sclerosis; Sitagliptin; Solid Organ Transplant; Bone Marrow Stem Cell; Autologous Hematopoietic Stem Cell Transplantion;
D O I
10.1186/1758-5996-1-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide beta cell regeneration. Conclusion: High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce complete remission (insulin independence) in most patients with early onset type 1 diabetes mellitus.
引用
收藏
页数:4
相关论文
共 50 条
  • [21] Stem cell transplantation for the treatment of patients with type 1 diabetes mellitus: A meta-analysis
    Gan, Jiadi
    Wang, Yingjin
    Zhou, Xiaodong
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 16 (06) : 4479 - 4492
  • [22] Transplantation of mesenchymal stem cells improves type 1 diabetes mellitus
    Lisha Li
    Furong Li
    Feng Gao
    Yali Yang
    Yuanyuan Liu
    Pingping Guo
    Yulin Li
    Cell and Tissue Research, 2016, 364 : 345 - 355
  • [23] Transplantation of mesenchymal stem cells improves type 1 diabetes mellitus
    Li, Lisha
    Li, Furong
    Gao, Feng
    Yang, Yali
    Liu, Yuanyuan
    Guo, Pingping
    Li, Yulin
    CELL AND TISSUE RESEARCH, 2016, 364 (02) : 345 - 355
  • [24] Stem cell approaches for the treatment of type 1 diabetes mellitus
    Wagner, Ryan T.
    Lewis, Jennifer
    Cooney, Austin
    Chan, Lawrence
    TRANSLATIONAL RESEARCH, 2010, 156 (03) : 169 - 179
  • [25] Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Type 1 Diabetes Mellitus Patients
    dos Santos, Manoel Antonio
    Salome Silva, Amanda Ferraz
    de Oliveira-Cardoso, Erika Arantes
    Mastropietro, Ana Paula
    Voltarelli, Julio Cesar
    PSICOLOGIA-REFLEXAO E CRITICA, 2011, 24 (02): : 264 - 271
  • [26] Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus Reply
    Voltarelli, Julio C.
    Martinez, Edson Z.
    Burt, Richard K.
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (06): : 624 - 625
  • [27] Comparison of Therapeutic Characteristics of Islet Cell Transplantation Simultaneous with Pancreatic Mesenchymal Stem Cell Transplantation in Rats with Type 1 Diabetes Mellitus
    Unsal, Ilknur Ozturk
    Ginis, Zeynep
    Pinarli, Ferda Alparslan
    Albayrak, Aynur
    Cakal, Erman
    Sahin, Mustafa
    Delibasi, Tuncay
    STEM CELL REVIEWS AND REPORTS, 2015, 11 (03) : 526 - 532
  • [28] Comparison of Therapeutic Characteristics of Islet Cell Transplantation Simultaneous with Pancreatic Mesenchymal Stem Cell Transplantation in Rats with Type 1 Diabetes Mellitus
    Ilknur Ozturk Unsal
    Zeynep Ginis
    Ferda Alparslan Pinarli
    Aynur Albayrak
    Erman Cakal
    Mustafa Sahin
    Tuncay Delibasi
    Stem Cell Reviews and Reports, 2015, 11 : 526 - 532
  • [29] Efficacy of mesenchymal stem cell transplantation therapy for type 1 and type 2 diabetes mellitus: a meta-analysis
    Yanju Li
    Feiqing Wang
    Huiling Liang
    Dongxin Tang
    Mei Huang
    Jianing Zhao
    Xu Yang
    Yanqing Liu
    Liping Shu
    Jishi Wang
    Zhixu He
    Yang Liu
    Stem Cell Research & Therapy, 12
  • [30] Efficacy of mesenchymal stem cell transplantation therapy for type 1 and type 2 diabetes mellitus: a meta-analysis
    Li, Yanju
    Wang, Feiqing
    Liang, Huiling
    Tang, Dongxin
    Huang, Mei
    Zhao, Jianing
    Yang, Xu
    Liu, Yanqing
    Shu, Liping
    Wang, Jishi
    He, Zhixu
    Liu, Yang
    STEM CELL RESEARCH & THERAPY, 2021, 12 (01)