Rhodium-catalyzed ortho-acrylation of aryl ketone O-methyl oximes with cyclopropenones

被引：6
|
作者：
Liu, Yafeng [1 ]
Tian, Yuan [1 ]
Su, Kexin [1 ]
Guo, Xin [2 ]
Chen, Baohua [1 ]
机构：
[1] Lanzhou Univ, Dept Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, State Key Lab Appl Organ Chem, Lanzhou, Gansu, Peoples R China
[2] North Minzu Univ, Sch Chem & Chem Engn, Yinchuan, Ningxia, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2020年 / 18卷 / 20期
关键词：
C-H BONDS; CHALCONE DERIVATIVES; OLEFINATION REACTION; MILD SYNTHESIS; ACYLATION; KETOXIMES; ARENES; ACTIVATION; CARBANIONS; MECHANISM;
D O I：
10.1039/d0ob00064g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient Rh-catalyzed ortho-acrylation reaction for the synthesis of chalcones from O-methyl ketoximes and cyclopropenones via C-H bond activation has been described. This cross-coupling reaction exhibits high functional group tolerance and regioselectivity. A wide range of chalcone derivatives are obtained in moderate to good yields under mild conditions.
引用
收藏
页码：3823 / 3826
页数：4
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