Polymorphism in the promoter region of the tumor necrosis factor-alpha gene in cattle herds naturally infected and uninfected with the Bovine Leukemia Virus

被引：11
|
作者：
Bojarojc-Nosowicz, B. [1 ]
Kaczmarczyk, E. [1 ]
Stachura, A. [1 ]
Kotkiewicz, M. [1 ]
机构：
[1] Univ Warmia & Mazury Olsztyn, Dept Anim Genet, PL-10719 Olsztyn, Poland
来源：
POLISH JOURNAL OF VETERINARY SCIENCES | 2011年 / 14卷 / 04期
关键词：
gene; TNF-alpha; polymorphism; leukosis; lymphocytes; bovine leukemia virus;
D O I：
10.2478/v10181-011-0101-0
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The objective of this study was to describe and compare the genetic structure (TNF-alpha -position 824) of dairy cattle herds infected and not infected with the bovine leukemia virus (BLV). The results of the present study indicate that BLV-positive herds were characterized by similar genetic structure (TNF-alpha -824A/G). The genetic equilibrium in these herds was preserved, but a tendency to increased frequency of GIG homozygotes was found. The genetic structure of the healthy herd differed considerably from that of leukemic herds.
引用
收藏
页码：671 / 673
页数：3
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