Neoadjuvant giredestrant (GDC-9545) + palbociclib versus anastrozole plus palbociclib in postmenopausal women with estrogen receptor-positive, HER2-negative, untreated early breast cancer: Primary analysis of the randomized, open-label, phase II coopERA breast cancer study

被引:0
|
作者
Hurvitz, Sara A.
Quiroga, Vanesa
Park, Yeon Hee
Bardia, Aditya
Lopez-Valverde, Vanesa
Steinseifer, Jutta
Fernando, Tharu M.
Spera, Gonzalo
Xue, Cloris
Fasching, Peter A.
机构
关键词
D O I
10.1158/1538-7445.SABCS21-PD13-06
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PD13-06
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Phase Ia/b Study of Giredestrant ± Palbociclib and ± Luteinizing Hormone-Releasing Hormone Agonists in Estrogen Receptor-Positive, HER2-Negative, Locally Advanced/Metastatic Breast Cancer
    Jhaveri, Komal L.
    Bellet, Meritxell
    Turner, Nicholas C.
    Loi, Sherene
    Bardia, Aditya
    Boni, Valentina
    Sohn, Joohyuk
    Neilan, Tomas G.
    Villanueva-Vazquez, Rafael
    Kabos, Peter
    Garcia-Estevez, Laura
    Lopez-Miranda, Elena
    Perez-Fidalgo, J. Alejandro
    Perez-Garcia, Jose M.
    Yu, Jiajie
    Fredrickson, Jill
    Moore, Heather M.
    Chang, Ching-Wei
    Bond, John W.
    Eng-Wong, Jennifer
    Gates, Mary R.
    Lim, Elgene
    CLINICAL CANCER RESEARCH, 2024, 30 (04) : 754 - 766
  • [22] Treatment efficacy of ribociclib or palbociclib plus letrozole in hormone receptor-positive/HER2-negative metastatic breast cancer
    Kahraman, Seda
    Erul, Enes
    Seyyar, Mustafa
    Gumusay, Ozge
    Bayram, Ertugrul
    Demirel, Burcin Cakan
    Acar, Omer
    Aksoy, Sercan
    Baytemur, Naziyet Kose
    Sahin, Elif
    Cabuk, Devrim
    Basaran, Gul
    Paydas, Semra
    Yaren, Arzu
    Guven, Deniz Can
    Erdogan, Atike Pinar
    Demirci, Umut
    Yasar, Alper
    Bayoglu, Ibrahim Vedat
    Hizal, Mutlu
    Gulbagci, Burcu
    Paksoy, Nail
    Davarci, Sena Ece
    Yilmaz, Funda
    Dogan, Ozlem
    Orhan, Sibel Oyucu
    Kayikcioglu, Erkan
    Aytac, Ali
    Keskinkilic, Merve
    Mocan, Eda Eylemer
    Unal, Olcun Umit
    Aydin, Esra
    Yucel, Hakan
    Isik, Deniz
    Eren, Onder
    Uluc, Basak Oyan
    Ozcelik, Melike
    Hacibekiroglu, Ilhan
    Aydiner, Adnan
    Demir, Hacer
    Oksuzoglu, Berna
    Cilbir, Ebru
    Cubukcu, Erdem
    Cetin, Bulent
    Oktay, Esin
    Erol, Cihan
    Okutur, Sadi Kerem
    Yildirim, Nilgun
    Alkan, Ali
    Selcukbiricik, Fatih
    FUTURE ONCOLOGY, 2023, : 727 - 736
  • [23] Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial
    Johnston, Stephen
    Puhalla, Shannon
    Wheatley, Duncan
    Ring, Alistair
    Barry, Peter
    Holcombe, Chris
    Boileau, Jean Francois
    Provencher, Louise
    Robidoux, Andre
    Rimawi, Mothaffar
    McIntosh, Stuart A.
    Shalaby, Ibrahim
    Stein, Robert C.
    Thirlwell, Michael
    Dolling, David
    Morden, James
    Snowdon, Claire
    Perry, Sophie
    Cornman, Chester
    Batten, Leona M.
    Jeffs, Lisa K.
    Dodson, Andrew
    Martins, Vera
    Modi, Arjun
    Osborne, C. Kent
    Pogue-Geile, Katherine L.
    Cheang, Maggie Chon U.
    Wolmark, Norman
    Julian, Thomas B.
    Fisher, Kate
    MacKenzie, Mairead
    Wilcox, Maggie
    Bartlett, Cynthia Huang
    Koehler, Maria
    Dowsett, Mitch
    Bliss, Judith M.
    Jacobs, Samuel A.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (03) : 178 - +
  • [24] COST-EFFECTIVENESS ANALYSIS OF PALBOCICLIB PLUS FULVESTRANT VERSUS EVEROLIMUS PLUS EXEMESTAN IN THE TREATMENT OF ESTROGEN RECEPTOR-POSITIVE, HER2-NEGATIVE, ADVANCED BREAST CANCER IN IRAN
    Taheri, S.
    Majd, Karimi Z.
    Rezaei, S.
    Yousefi, N.
    Peiravian, F.
    VALUE IN HEALTH, 2019, 22 : S472 - S472
  • [25] Overall survival with palbociclib plus endocrine therapy versus capecitabine in postmenopausal patients with hormone receptor-positive, HER2-negative metastatic breast cancer in the PEARL study
    Martin, Miguel
    Zielinski, Christoph
    Ruiz-Borrego, Manuel
    Carrasco, Eva
    Ciruelos, Eva M.
    Munoz, Montserrat
    Bermejo, Begona
    Margeli, Mireia
    Csoszi, Tibor
    Anton, Antonio
    Turner, Nicholas
    Casas, Maria, I
    Morales, Serafin
    Alba, Emilio
    Calvo, Lourdes
    De La Haba-Rodriguez, Juan
    Ramos, Manuel
    Murillo, Laura
    Santaballa, Ana
    Alonso-Romero, Jose L.
    Sanchez-Rovira, Pedro
    Corsaro, Massimo
    Huang, Xin
    Thallinger, Christiane
    Kahan, Zsuzsanna
    Gil-Gil, Miguel
    EUROPEAN JOURNAL OF CANCER, 2022, 168 : 12 - 24
  • [26] acelERA Breast Cancer (BC): Phase II study evaluating efficacy and safety of giredestrant (GDC-9545) versus physician's choice of endocrine monotherapy in patients (pts) with estrogen receptor-positive, HER2-negative (ER+/HER2-) locally advanced or metastatic breast cancer (LA/mBC).
    Martin, Miguel
    Lim, Elgene
    Mac Gregor, Mariana Chavez
    Shivhare, Mahesh
    Ross, Graham
    Patre, Monika
    Roncoroni, Laura
    Louka, Maria
    Sohn, Joohyuk
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [27] Neoadjuvant Chemotherapy with Concurrent Letrozole for Estrogen Receptor-Positive and HER2-Negative Breast Cancer: An Open-Label, Single-Center, Nonrandomized Phase II Study (NeoCHAI)
    Chae, Heejung
    Sim, Sung Hoon
    Kwon, Youngmi
    Lee, Eun-Gyeong
    Han, Jai Hong
    Jung, So-Youn
    Lee, Seeyoun
    Kang, Han-Sung
    Kim, Yeon-Joo
    Kim, Tae Hyun
    Lee, Keun Seok
    CANCERS, 2024, 16 (18)
  • [28] Expanded-Access Study of Palbociclib in Combination With Letrozole for Treatment of Postmenopausal Women With Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
    Stearns, Vered
    Brufsky, Adam M.
    Verma, Shailendra
    Cotter, Matthew J.
    Lu, Dongrui R.
    Dequen, Florence
    Joy, Anil Abraham
    CLINICAL BREAST CANCER, 2018, 18 (06) : E1239 - E1245
  • [29] Evaluation of pharmacodynamic (PD) and biologic activity in a preoperative window-of-opportunity (WOO) study of giredestrant (GDC-9545) in postmenopausal patients (pts) with estrogen receptor-positive, HER2-negative (ER+/HER2-) operable breast cancer (BC).
    Moore, Heather M.
    Boni, Valentina
    Bellet, Meritxell
    De Las Heras, Begona Bermejo
    Cortes, Maria Gion
    Oakman, Catherine
    Schmid, Peter
    Trinh, Xuan Bich
    Wheatley, Duncan
    Jhaveri, Komal L.
    Kabos, Peter
    Lim, Elgene
    Velu, Thierry
    Metcalfe, Ciara
    Gates, Mary R.
    Chang, Ching-Wei
    Bond, John
    Goldstein, Leonard D.
    Lauchle, Jennifer O'Hara
    Bardia, Aditya
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [30] An Open-label Phase I Study of GDC-0927 in Postmenopausal Women with Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer
    Chandarlapaty, Sarat
    Dickler, Maura N.
    Fidalgo, Jose Alejandro Perez
    Villanueva-Vazquez, Rafael
    Giltnane, Jennifer
    Gates, Mary
    Chang, Ching-Wei
    Cheeti, Sravanthi
    Fredrickson, Jill
    Wang, Xiaojing
    Collier, Ann
    Moore, Heather M.
    Metcalfe, Ciara
    Lauchle, Jennifer
    Humke, Eric W.
    Bardia, Aditya
    CLINICAL CANCER RESEARCH, 2023, 29 (15) : 2781 - 2790