Tumor suppressor death-associated protein kinase inhibits Th17 by targeting cytoplasmic HIF-1α for degradation

被引:0
|
作者
Chou, T. -F [1 ,2 ]
Chuang, Y. -T [3 ]
Hsieh, W. -C [1 ]
Chang, P. -Y [1 ]
Hsu, T. -S [1 ]
Miaw, S. -C [4 ]
Chen, R. -H [5 ]
Kimchi, A. [6 ]
Lai, M. -Z [1 ]
机构
[1] Acad Sinica, Inst Mol Biol, Taipei, Taiwan
[2] Natl Def Med Coll, Inst Life Sci, Taipei, Taiwan
[3] Natl Taiwan Univ Hosp, Dept Med Res, Taipei, Taiwan
[4] Natl Taiwan Univ, Inst Immunol, Taipei, Taiwan
[5] Acad Sinica, Inst Biol Chem, Taipei, Taiwan
[6] Weizmann Inst Sci, Dept Mol Genet, Rehovot, Israel
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
3542
引用
收藏
页码:523 / 523
页数:1
相关论文
共 50 条
  • [21] Increased HIF-1α expression in T cells and associated with enhanced Th17 pathway in systemic lupus erythematosus
    Liao, Hsiu-Jung
    Chu, Ching-Liang
    Wang, Szu-Chieh
    Lee, Hua-Yi
    Wu, Chien-Sheng
    JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 2022, 121 (12) : 2446 - 2456
  • [22] The Tumor Suppressor Death Associated Protein Kinase Inhibits TCR-activated NF-κB
    Chuang, Ya-Ting
    Lai, Ming-Zong
    CLINICAL IMMUNOLOGY, 2010, 135 : S124 - S124
  • [23] Death-associated protein kinase 1 variation and Parkinson's disease
    Dachsel, J. C.
    Wider, C.
    Vilarino-Gueell, C.
    Aasly, J. O.
    Rajput, A.
    Rajput, A. H.
    Lynch, T.
    Craig, D.
    Krygowska-Wajs, A.
    Jasinska-Myga, B.
    Opala, G.
    Barcikowska, M.
    Czyzewski, K.
    Wu, R. -M.
    Heckman, M. G.
    Uitti, R. J.
    Wszolek, Z. K.
    Farrer, M. J.
    Ross, O. A.
    EUROPEAN JOURNAL OF NEUROLOGY, 2011, 18 (08) : 1090 - 1093
  • [24] Discovery and optimization of isoliquiritigenin as a death-associated protein kinase 1 inhibitor
    Yokoyama, Takeshi
    Hisatomi, Kotono
    Oshima, Saki
    Tanaka, Ichiro
    Okada, Takuya
    Toyooka, Naoki
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 279
  • [25] Death-Associated Protein Kinase 1 Phosphorylation in Neuronal Cell Death and Neurodegenerative Disease
    Kim, Nami
    Chen, Dongmei
    Zhou, Xiao Zhen
    Lee, Tae Ho
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (13):
  • [26] Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein (vol 271, pg 144, 2013)
    Song, Xiuming
    Yao, Jing
    Wang, Fei
    Zhou, Mi
    Zhou, Yuxin
    Wang, Hu
    Wei, Libin
    Zhao, Li
    Li, Zhiyu
    Lu, Na
    Guo, Qinglong
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 384
  • [27] Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder
    Xiao-Hui Li
    Hong-Can Zhu
    Xue-Min Cui
    Wang Wang
    Lin Yang
    Li-Bo Wang
    Neng-Wei Hu
    Dong-Xiao Duan
    NeuralRegenerationResearch, 2023, 18 (08) : 1795 - 1801
  • [28] Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder
    Li, Xiao-Hui
    Zhu, Hong-Can
    Cui, Xue-Min
    Wang, Wang
    Yang, Lin
    Wang, Li-Bo
    Hu, Neng-Wei
    Duan, Dong-Xiao
    NEURAL REGENERATION RESEARCH, 2023, 18 (08) : 1795 - 1801
  • [29] Death-associated protein kinase 1 as a therapeutic target for Alzheimer's disease
    Zhang, Tao
    Kim, Byeong Mo
    Lee, Tae Ho
    TRANSLATIONAL NEURODEGENERATION, 2024, 13 (01)
  • [30] HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease
    Xie, Anyan
    Robles, Rene J.
    Mukherjee, Samiran
    Zhang, Haohai
    Feldbruegge, Linda
    Csizmadia, Eva
    Wu, Yan
    Enjyoji, Keiichi
    Moss, Alan C.
    Otterbein, Leo E.
    Quintana, Francisco J.
    Robson, Simon C.
    Longhi, Maria Serena
    JOURNAL OF AUTOIMMUNITY, 2018, 94 : 122 - 133