Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer

被引：26

作者：

Wang, Min

Lacy, Gabrielle

Gao, Mingzhang

Miller, Kathy D.

Sledge, George W.

Zheng, Qi-Huang ^{[1
]}

机构：

[1] Indiana Univ, Sch Med, Dept Radiol, Indianapolis, IN 46202 USA

[2] Indiana Univ, Sch Med, Dept Med, Indianapolis, IN 46202 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2007年 / 17卷 / 02期

关键词：

sulfonanilide analogues; carbon-11; positron emission tomography (PET); aromatase; breast cancer;

D O I：

10.1016/j.bmcl.2006.10.065

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[C-11]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamides ([C-11]3a-f, alkyl = propyl, isopropyl, 1-ethyl-propyl, cyclopentyl, cyclohexyl, and cyclohexylethyl), were designed and synthesized as potential PET agents for imaging of aromatase in breast cancer. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：332 / 336

页数：5

共 50 条

[41] Synthesis and biological distribution study of a new carbon-11 labeled porphyrin for PET imaging. Photochemical and biological characterization of the non-labeled porphyrin
Goncalves, Nuno P. F.
Simoes, Ana V. C.
Abreu, Artur R.
Abrunhosa, Antero J.
Dabrowski, Janusz M.
Pereira, Mariette M.
[J]. JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 2015, 19 (08) : 946 - 955
[42] Imaging the distribution of Carbon-11 labeled rifampicin, isoniazid and pyrazinamide in baboons using PET
Liu, Li
Xu, Youwen
Shea, Colleen
Fowler, Joanna
Hooker, Jacob
Tonge, Peter
[J]. JOURNAL OF NUCLEAR MEDICINE, 2011, 52
[43] Imaging the Distribution of Carbon-11 Labeled Rifampicin, Isoniazid and Pyrazinamide in Baboons using PET
Liu, Li
Hooker, Jacob M.
Fowler, Joanna S.
Tonge, Peter J.
[J]. FASEB JOURNAL, 2010, 24
[44] Synthesis of a carbon-11 labeled conformationally restricted rivastigmine analog for PET imaging of heart enzymes AChE and BChE
Wang, Min
Wang, Ji-Quan
Gao, Mingzhang
Zheng, Qi-Huang
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233 : 536 - 536
[45] Toward PET imaging of A2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer Synthesis and imaging of a new A2B PET tracer
Petroni, Debora
Giacomelli, Chiara
Taliani, Sabrina
Barresi, Elisabetta
Robello, Marco
Daniele, Simona
Bartoli, Antonietta
Burchielli, Silvia
Pardini, Silvia
Salvadori, Piero A.
Da Settimo, Federico
Martini, Claudia
Trincavelli, Maria Letizia
Menichetti, Luca
[J]. NUCLEAR MEDICINE AND BIOLOGY, 2016, 43 (05) : 309 - 317
[46] Synthesis of carbon-11-labeled 4-aryl-4H-chromens as new PET agents for imaging of apoptosis in cancer
Gao, Mingzhang
Wang, Min
Miller, Kathy D.
Hutchins, Gary D.
Zheng, Qi-Huang
[J]. APPLIED RADIATION AND ISOTOPES, 2010, 68 (01) : 110 - 116
[47] Synthesis of a carbon-11 labeled metabotropic glutamate receptor 7 ligand for PET neuroimaging
Xiao, Zhiwei
Zhao, Chunyu
Haider, Ahmed
Rong, Jian
Zhang, Ming-Rong
Liang, Steven
[J]. NUCLEAR MEDICINE AND BIOLOGY, 2022, 108 : S112 - S112
[48] Radiosynthesis of a carbon-11 labeled tetrahydrobenzisoxazole derivative as a new PET probe for γ-secretase imaging in Alzheimer's disease
Xu, Zhidong
Miao, Caihong
Dong, Fugui
Jia, Limeng
Li, Wei
Wang, Min
Liu, Wenqing
Zheng, Qi-Huang
[J]. APPLIED RADIATION AND ISOTOPES, 2020, 155
[49] MEDI 210-Synthesis of new carbon-11 labeled carboxamides as PET radioligands for imaging of dopamine D3 receptor
Gao, Mingzhang
Wang, Min
Zheng, Qi-Huang
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
[50] Synthesis of carbon-11-labeled tricyclic necroptosis inhibitors as new potential PET agents for imaging of tumor necrosis factor α (TNF-α)
Gao, Mingzhang
Lola, Christian M.
Wang, Min
Miller, Kathy D.
Sledge, George W.
Hutchins, Gary D.
Zheng, Qi-Huang
[J]. APPLIED RADIATION AND ISOTOPES, 2010, 68 (10) : 1950 - 1958

← 1 2 3 4 5 →