The association between respiratory syncytial virus infection and reactive airway disease

被引：25
|
作者：
Piedimonte, G
机构：
[1] Univ Miami, Sch Med, Dept Pediat, Miami, FL USA
[2] Univ Miami, Sch Med, Dept Med, Miami, FL USA
[3] Univ Miami, Sch Med, Dept Mol Cellular Pharmacol, Miami, FL USA
来源：
RESPIRATORY MEDICINE | 2002年 / 96卷
关键词：
asthma; palivizumab; paediatrics; prevention;
D O I：
10.1053/rmed.2002.1297
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Evidence has been accumulating that respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) in infants may be linked to subsequent development of reactive airway disease (RAD) in childhood, and therefore research into the prevention of RSV LRTI may have important implications for the prevention of RAD. This article reviews the epidemiological evidence linking RSV and RAID and some of the theories concerning cellular and molecular mechanisms of post-viral airway inflammation in order to understand how RSV prophylaxis may assist in reducing the occurrence of RSV LRTI and RAD. (C) 2002 Elsevier Science Ltd.
引用
收藏
页码：S25 / S29
页数：5
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