Synthesis of (R)-(+)-hippospongic acid A, a triterpene isolated from the marine sponge, Hippospongia sp.

被引：5

作者：

Ichihashi, M ^{[1
]}

Takikawa, H ^{[1
]}

Mori, K ^{[1
]}

机构：

[1] Sci Univ Tokyo, Dept Chem, Shinjuku Ku, Tokyo 1628601, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2001年 / 65卷 / 11期

关键词：

marine natural product; enantioselective synthesis; triterpenoid; enzymatic resolution;

D O I：

10.1271/bbb.65.2569

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hippospongic acid A (1) is a triterpene metabolite of the marine sponge, Hippospongia sp., with inhibitory activity against the gastrulation of starfish embryos. (R)-(+)-1 was synthesized by employing enzymatic kinetic resolution as the key step.

引用

页码：2569 / 2572

页数：4

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