Synthesis of 5-alkyl(aryl)-2-alkylsulfanyl(alkoxy)-4-hydroxy-6H-1,3-oxazin-6-ones

被引：4
|
作者：
Lalaev, BY [1 ]
Yakovlev, IP [1 ]
Zakhs, VE [1 ]
机构：
[1] St Petersburg State Chem & Pharmaceut Acad, St Petersburg, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2005年 / 75卷 / 03期
关键词：
Ether; Benzene; Toluene; Boiling; Diethyl;
D O I：
10.1007/s11176-005-0245-7
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Alkyl carbarnates and S-alkyl thiocarbamates react with substituted malonyl dichlorides in boiling benzene to give the corresponding 2,5-substituted 4-hydroxy-6H-1,3-oxazin-6-ones. The reaction of S-methyl thiocarbamate with unsubstituted malonyl dichloride in boiling diethyl ether or benzene leads to formation of S-methyl (3-methylsulfanylaminocarbonyl-3-oxopropionyl)thiocarbamate and is not accompanied by cyclization, whereas in boiling toluene 4-hydroxy-2-methylsulfanyl-6H-1,3-oxazin-6-one is obtained.
引用
收藏
页码：432 / 436
页数：5
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