Eosinophilic asthma with chronic rhinosinusitis/nasal polyps and biologic agents

被引：6
|
作者：
Yilmaz, Insu [1 ]
机构：
[1] Erciyes Univ, Fac Med, Dept Chest Dis, Div Immunol & Allerg Dis, Kayseri, Turkey
来源：
TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX | 2019年 / 67卷 / 04期
关键词：
Severe asthma; eosinophilic asthma; chronic rhinosinusitis/nasal polyp; asthma phenotype; biologics; AIRWAY INFLAMMATION; NASAL POLYPS; PHENOTYPES; BENRALIZUMAB; EFFICACY; PHASE-3; IL-5; IDENTIFICATION; MEPOLIZUMAB; EXPRESSION;
D O I：
10.5578/tt.68953
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The current understanding in severe asthma management is the targeted therapy approach with the evaluation of phenotypes and biomarkers. Therefore, personalized treatments are recently more prominent. Eosinophilic asthma with chronic rhinosinusitis/nasal polyps (CRSwNP) is one of the severe asthma phenotypes which needs a personalized treatment approach. Biological agents which specifically target type 2 (T2) high inflammation have been used in this severe asthma phenotype with a preferable safety profile. In the present review, biological agents in eosinophilic asthma with CRSwNP will be discussed.
引用
收藏
页码：292 / 299
页数：8
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