Flexibility and Reactivity in Promiscuous Enzymes

被引:36
|
作者
Gatti-Lafranconi, Pietro [1 ]
Hollfelder, Florian [1 ]
机构
[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England
基金
英国生物技术与生命科学研究理事会;
关键词
conformation analysis; enzyme promiscuity; enzyme superfamily; evolution; phosphate transfer; SUBSTITUTED CARBONIC-ANHYDRASE; CATALYTIC PROMISCUITY; ALKALINE-PHOSPHATASE; CONFORMATIONAL SELECTION; ACTIVE-SITE; SUBSTRATE-SPECIFICITY; T4; LYSOZYME; INDUCED FIT; PROTEIN; EVOLUTION;
D O I
10.1002/cbic.201200628
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:285 / 292
页数:8
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