Efficient Terpene Synthase Catalysis by Extraction in Flow

被引：12
|
作者：
Cascon, Oscar [1 ]
Richter, Gerald [1 ]
Allemann, Rudolf K. [1 ]
Wirth, Thomas [1 ]
机构：
[1] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales
来源：
CHEMPLUSCHEM | 2013年 / 78卷 / 11期
关键词：
continuous flow synthesis; extraction; sesquiterpenes; sonication; terpene synthases; SEGMENTED FLUID-FLOW; PRE-STEADY-STATE; ARISTOLOCHENE; MICROREACTOR;
D O I：
10.1002/cplu.201300303
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Flowing enzymes: Continuous extraction of products enhances the enzymatic productivity of sesquiterpenes (see figure). Even unnatural substrates are tolerated leading to valuable unnatural target molecules in superior yields compared with batch protocols. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：1334 / 1337
页数：4
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