Management of Recurrent Thrombosis in Antiphospholipid Syndrome

被引：27

作者：

Nalli, Cecilia ^{[1
,2
,3
]}

Andreoli, Laura ^{[1
,2
]}

Casu, Cinzia ^{[4
]}

Tincani, Angela ^{[1
,2
]}

机构：

[1] Spedali Civil Brescia, Dept Clin & Expt Sci, I-25125 Brescia, Italy

[2] Univ Brescia, Brescia, Italy

[3] Univ Pavia, Rheumatol Chair, I-27100 Pavia, Italy

[4] Osped Niguarda Ca Granda, Rheumatol Unit, Milan, Italy

来源：

CURRENT RHEUMATOLOGY REPORTS | 2014年 / 16卷 / 03期

关键词：

Antiphospholipid antibodies; Anticardiolipin antibodies; Anti-ss 2glycoprotein I antibodies; Lupus anticoagulant; Thrombosis; Recurrent thrombosis; Stroke; Primary antiphospholipid syndrome; Cardiovascular risk; SYSTEMIC-LUPUS-ERYTHEMATOSUS; DEEP VENOUS THROMBOSIS; RISK-FACTORS; ANTICARDIOLIPIN ANTIBODIES; ANTICOAGULATION TREATMENT; CLINICAL-COURSE; TASK-FORCE; PREVENTION; APS; MULTICENTER;

D O I：

10.1007/s11926-013-0405-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

One of the challenges of managing patients with antiphospholipid syndrome is the prevention of rethrombosis (secondary prophylaxis). Risk stratification, i.e. traditional cardiovascular and thrombosis risk factors, systemic autoimmune diseases, antiphospholipid antibody profile, and the intensity of anticoagulation are all relevant to the management of APS patients with recurrent thrombosis. The paper will review "state of the art" strategies for optimizing therapy for APS patients with recurrent thrombosis.

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页数：8

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