A short synthesis of trans-(+)-laurediol

被引:21
|
作者
Martín, T [1 ]
Martín, VS [1 ]
机构
[1] Univ La Laguna, Inst Univ Bioorgan Antonio Gonzalez, E-38206 Tenerife, Spain
关键词
marine metabolites; Sharpless asymmetric dihydroxylation reaction; asymmetric synthesis;
D O I
10.1016/S0040-4039(00)00190-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A highly convergent and short synthesis of trans-(+)-laurediol is presented. The synthesis features a highly efficient construction of a cis-3-hydroxy-butyrolactone through a Sharpless AD reaction of a beta, unsaturated ester. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2503 / 2505
页数:3
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