Model T Muscle CARs Can Treat Brain Tumors

被引：2

作者：

Johnson, Laura A. ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Brain Tumor Immunotherapy Program, Neurosurg Div,Dept Surg, Durham, NC 27710 USA

来源：

CLINICAL CANCER RESEARCH | 2012年 / 18卷 / 21期

关键词：

CELLS; PERSISTENCE; MELANOMA; RECEPTOR; THERAPY; ANTIGEN;

D O I：

10.1158/1078-0432.CCR-12-2627

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Despite standard treatment with resection, radiation, and chemotherapy, glioblastoma remains a deadly disease with a dismal prognosis. Redirecting patient T cells to target the glioblastoma-associated antigen, IL13R alpha 2, offers a promising translational immunotherapy with the potential to make a meaningful impact for patients with this disease. Clin Cancer Res; 18(21); 5834-6. (C) 2012 AACR.

引用

页码：5834 / 5836

页数：3

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