Model T Muscle CARs Can Treat Brain Tumors

被引：2
|
作者：
Johnson, Laura A. [1 ]
机构：
[1] Duke Univ, Med Ctr, Brain Tumor Immunotherapy Program, Neurosurg Div,Dept Surg, Durham, NC 27710 USA
来源：
CLINICAL CANCER RESEARCH | 2012年 / 18卷 / 21期
关键词：
CELLS; PERSISTENCE; MELANOMA; RECEPTOR; THERAPY; ANTIGEN;
D O I：
10.1158/1078-0432.CCR-12-2627
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Despite standard treatment with resection, radiation, and chemotherapy, glioblastoma remains a deadly disease with a dismal prognosis. Redirecting patient T cells to target the glioblastoma-associated antigen, IL13R alpha 2, offers a promising translational immunotherapy with the potential to make a meaningful impact for patients with this disease. Clin Cancer Res; 18(21); 5834-6. (C) 2012 AACR.
引用
收藏
页码：5834 / 5836
页数：3
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