Treating myeloma: the future is already here!

被引：8
|
作者：
Landgren, Ola [1 ]
Korde, Neha [1 ]
机构：
[1] Natl Canc Inst, Milan, Italy
来源：
BLOOD | 2012年 / 120卷 / 09期
关键词：
MULTIPLE-MYELOMA; THERAPY;
D O I：
10.1182/blood-2012-06-434571
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Jakubowiak and colleagues report outstanding results from a phase 1/2 study using carfilzomib-a next-generation proteasome inhibitor that selectively and irreversibly binds to the proteasome, targeting chymotrypsin-like activity-in combination with lenalidomide and low-dose dexamethasone in newly diagnosed multiple myeloma patients. The study shows excellent response rates, deep and durable responses, continued responses during treatment, and limited severe toxicities.(1)
引用
收藏
页码：1754 / 1756
页数：5
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