Prevalence and Risk Factors of Nasopharyngeal Carriage of Streptococcus pneumoniae in Healthy Children in Japan

被引：10

作者：

Ueno, Masahiro ^{[1
,2
]}

Ishii, Yoshikazu ^{[3
]}

Tateda, Kazuhiro ^{[3
]}

Anahara, Yoshiko ^{[4
]}

Ebata, Akiko ^{[4
]}

Iida, Masaei ^{[4
]}

Inamura, Seiko ^{[5
]}

Takahata, Kahori ^{[6
]}

Suzuki, Yoko ^{[6
]}

Chang, Bin ^{[7
]}

Wada, Akihito ^{[7
,8
]}

Sugita, Minoru ^{[2
]}

Tanaka, Taichiro ^{[2
]}

Nishiwaki, Yuji ^{[2
]}

机构：

[1] Hasuda Issinkai Hosp, Dept Pediat, Saitama 3490123, Japan

[2] Toho Univ, Sch Med, Dept Environm & Occupat Hlth, Tokyo 1438540, Japan

[3] Toho Univ, Sch Med, Dept Microbiol & Infect Dis, Tokyo 1438540, Japan

[4] Ageo Med Labs Inc, Dept Bacteriol, Saitama 3400808, Japan

[5] Yashio Ekimae Internal Med & Pediat Clin, Saitama 3400822, Japan

[6] Tokyo Womens Med Univ, Med Ctr East, Dept Pediat, Tokyo 1168567, Japan

[7] Natl Inst Infect Dis, Dept Bacteriol 1, Tokyo 1628640, Japan

[8] Yonaguni Med Clin, Okinawa 9071801, Japan

来源：

JAPANESE JOURNAL OF INFECTIOUS DISEASES | 2013年 / 66卷 / 01期

关键词：

CONJUGATE VACCINE; COMMUNITY; COLONIZATION;

D O I：

10.7883/yoken.66.22

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The findings of this study revealed a 22% prevalence of Streptococcus pneumoniae among healthy children in Japan; the prevalence tended to increase with age. We identified attendance at day-care facilities and the presence of older siblings as the major risk factors associated with pneumococcal carriage. A significant decrease in pneumococcal colonization was observed among children during the summer; however, a seasonal variation was independent of various factors. Our findings suggest that prior immunization with heptavalent pneumococcal conjugate vaccine within the current recommended schedule is required for children exposed to these risk factors.

引用

页码：22 / 25

页数：4

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