IFN-Independent STING Signaling: Friend or Foe?

被引:4
|
作者
Bohnert, Volker [1 ,2 ]
Ritchie, Christopher [1 ,2 ]
Li, Lingyin [1 ,2 ]
机构
[1] Stanford Univ, Dept Biochem, Stanford, CA 94305 USA
[2] Stanford Univ, Inst Chem Engn & Med Human Hlth ChEM H, Stanford, CA 94305 USA
关键词
D O I
10.1016/j.immuni.2020.06.021
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this issue, Wu et al. demonstrate the importance of the neglected interferon (IFN)-independent STING signaling axis in mice. They find that although this axis is important for antiviral HSV-1 resistance, it has a pro-cancer role by promoting T cell death.
引用
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页码:8 / 10
页数:4
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