A highly selective turn-on near-infrared fluorescent probe for hydrogen sulfide detection and imaging in living cells

被引:249
|
作者
Wang, Rui [1 ]
Yu, Fabiao [1 ]
Chen, Lingxin [1 ]
Chen, Hao [1 ]
Wang, Linjie [1 ]
Zhang, Weiwei [1 ]
机构
[1] Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
基金
中国国家自然科学基金;
关键词
H2S; REDUCTION; PERFUSION;
D O I
10.1039/c2cc36088h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We have described a turn-on near-infrared fluorescent probe Cy-NO2 based on nitro group reduction for intracellular H2S detection. The probe employs cyanine dye as a fluorophore, and is equipped with a nitro group as a fluorescent modulator. It is readily employed for assessing intracellular H2S level changes, and confocal imaging is achieved successfully.
引用
收藏
页码:11757 / 11759
页数:3
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