Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil

被引：4
|
作者：
Barbosa Damasceno, Carolina Sette [1 ]
de Oliveira, Leticia Freire [2 ]
Szabo, Ellis Marina [1 ]
Souza, Angela Maria [2 ]
Gaspari Dias, Josiane Fatima [2 ]
Miguel, Marilis Dalarmi [2 ]
Miguel, Obdulio Gomes [1 ]
机构：
[1] Univ Fed Parana, Lab Fitoquim, Dept Farm, Curitiba, Parana, Brazil
[2] Univ Fed Parana, Dept Farm, Lab Farmacotecn, Curitiba, Parana, Brazil
来源：
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2017年 / 53卷 / 04期
关键词：
Ocotea bicolor/Oilessential/chemical composition; Lauraceae; Antioxidant activity; Biological activity; LEAF ESSENTIAL OIL; CANCER CELLS; COSTA-RICA; IN-VITRO; EXTRACTS; BIOASSAY; ELEMENE;
D O I：
10.1590/s2175-97902017000417298
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The essential oil composition of the Ocotea bicolor, native plant of Brazil, was studied for the first time. The essential oil of the leaf was obtained by hydrodistillation and analyzed by GC/MS. The analytical procedure revealed a predominance of sesquiterpenes, delta-cadinene (7.39%), beta-sesquiphellandrene (6.67%), beta-elemene (5.41%) and alpha-cadinol (5,23%). The essential oil was submitted to brine shrimp toxicity evaluation, antioxidant and antibacterial tests. The antioxidant activity by the formation of phosphomolybdenum complex method presented positive results. The minimum inhibitory concentration (MIC) values were higher than 1000 mu g/mL for the microorganisms tested. Toxicity activity revealed LC50 results of 40.10 (mu g/mL), being toxic to the organisms in this study.
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页数：8
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